Circular dichroism (CD) spectroscopy is a spectroscopic technique that measures the CD of molecules over a wide range of wavelengths. CD spectroscopy is widely used to study chiral molecules of all shapes and sizes, but its most important applications are in the study of large biological molecules. Circular dichroism has a primary application in analyzing the secondary structure or conformation of macromolecules, particularly proteins. Because the secondary structure is sensitive to its environments, such as temperature or pH, circular dichroism can be used to observe how the secondary structure changes in response to environmental conditions or interactions with other molecules.
Circular dichroism (CD) spectrometers have become more widely known because of their benefits