1. Health

BOC Sciences Becomes the Largest PseudoUridine Supplier in the World

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BOC Sciences recently announces that its annual yield of pseudoUridine has reached more than 500 kilograms, which indicates that this US-based chemical and pharmaceutical company has become the largest supplier of pseudoUridine in the world.

Currently, due to the severe situation of the COVID-19 pandemic, the global need for vaccines is still huge. Under this circumstance, BOC Sciences has strengthened its supply capacity of pseudoUridine and derivatives to ease the pressure on the global supply of vaccine raw materials.

BOC Sciences has been known for its strong ability in the development, design, synthesis and production of nucleosides and nucleotides over the years. With its strong cGMP platform and highly-skilled research team, BOC Sciences can supply nucleotide products ranging from milligrams to kilograms, or even hundreds of kilograms. Among BOC Sciences's numerous nucleotide products, pseudoUridine and N1-MethylpseudoUridine have become superstar products due to their important roles in vaccine development and production.

PseudoUridine

PseudoUridine has a subtle but significant effect on the nearby sugar phosphate backbone and enhances base accumulation. It is considered to be a regulator of the latent process of the human immunodeficiency virus (HIV) infection. In addition to pseudoUridine, pseudoUridine derivatives such as 1-methylpseudoUridine, 3-methylpseudoUridine, 2′-O-methylpseudoUridine and ultramodified residue 1 -Methyl-3-(3-amino-3-carboxypropyl) pseudoUridine are also popular products of BOC Sciences.

N1-MethylpseudoUridine

The coronavirus has inspired effective vaccine development activities. N1-methylpseudoUridine is an RNA modification that can be used to improve the safety and effectiveness of the COVID-19 messenger RNA vaccine. As a well-known supplier of pharmaceutical raw materials in the industry, BOC Sciences has been committed to producing COVID-19 mRNA vaccine raw materials with high quality. N1-methylpseudoUridine, one of the raw materials for the COVID-19 mRNA vaccine, has recently become one of the best-selling products of BOC Sciences. In mRNA vaccines, the unnatural RNA nucleobase N1-methylpseudoUridine can enhance immune evasion and protein production. N1-methylpseudoUridine from BOC Sciences has been contributing to the current production of COVID-19 mRNA vaccines.

Furthermore, a wealth of pseudoUridine derivatives are available at BOC Sciences, such as phosphate pseudoUridine and phosphoramidite pseudoUridine. PseudoUridine series products can be applied to RNA modification. Its pseudoUridine series products can also be applied in the production of oligonucleotides.

BOC Sciences will be invited to attend the TIDES USA: Oligonucleotide & Peptide Therapeutics Conference which is to take place from September 20th through 23th at the Boston Convention and Exhibition Center.

For more information about BOC Sciences's pseudoUridine and derivatives, please visit the website: https://nucleotech.bocsci.com.

About BOC Sciences

BOC Sciences’s research team focuses on research in various industries, such as pharmaceuticals, chemistry, and life sciences. For more than a decade, BOC Sciences has been committed to offering strategies and solutions to help solve the industry's most pressing drug development problems, becoming the world's leading pseudoUridine supplier with the largest production capacity to promote vaccine development.

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