Osteoporosis, a metabolic bone disease characterised by poor bone density and degeneration of bone architecture that increases the risk of fractures, affects about 10 million men and women in the United States1. 2 Fractures caused by osteoporosis can increase pain, disability, nursing home placement, overall health care expenses, and death. 3 The primary method for diagnosing osteoporosis is to measure bone mineral density (BMD) with noninvasive dual-energy x-ray absorptiometry. Bisphosphonates, receptor activator of nuclear factor kappa-B ligand inhibitors, oestrogen agonists/antagonists, parathyroid hormone analogues, and calcitonin are examples of osteoporosis drugs. 3–6 A cathepsin K inhibitor and a monoclonal antibody against sclerostin are two emerging medicines that use unique techniques.
The adverse effects of Osteoporosis Drugs are projected to stifle expansion. Alendronate, for example, can cause stomach discomfort, acid reflux, constipation, diarrhoea, upset stomach, nausea, and muscular and joint pain. Furthermore, limited awareness and diagnosis of osteoporosis, particularly in emerging nations, is projected to constrain market expansion.
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