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A fibroid that grows to the outside of the uterus (a subserous myoma) can grow in such a way that it is only attached to the uterus with a stalk. Such a stalked myoma can rotate on its own axis. If it does not turn back by itself, the tissue may die because the blood vessels are pinched. This causes a very severe abdominal pain and must be operated soon with the various treatment of uterine fibroids options available. Other uterine fibroids problems include pain attacks caused by fibroids when they become so large and hinder the blood supply.

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