Disclaimer: This is a user generated content submitted by a member of the WriteUpCafe Community. The views and writings here reflect that of the author and not of WriteUpCafe. If you have any complaints regarding this post kindly report it to us.

Small vesicles about 40 nanometres (40×10-9 M) in size are formed by the Golgi PandemicSurvival Review  apparatus in the cell body of the motor neuron in the spinal cord. These vesicles are then transported by streaming of the axoplasm through the core of the axon from the central cell body of the spinal cord all the way to the neuromuscular junction at the tips of the nerve fibres. About 300,000 of these small vesicles collect in the nerve terminals of a single skeletal muscle end plate.

Acetylcholine is synthesized in the cytosol of the terminal nerve fibres but is then transported through the membranes of the vesicles to their interior, where it is stored in highly concentrated form, with about 10,000 molecules of acetylcholine in each vesicle.

Under resting conditions, an occasional vesicle fuses with the surface membrane of the nerve terminal and releases it's acetylcholine into the synaptic gutter. When this occurs, a so-called miniature end plate potential, about 0.4 mV in intensity and lasting for a few milliseconds, occurs in the local area of the muscle fibre because of the action of this ‘packet' of 10,000 acetylcholine molecules.

https://neighboursreview.com/pandemic-survival-review/

Login

Welcome to WriteUpCafe Community

Join our community to engage with fellow bloggers and increase the visibility of your blog.
Join WriteUpCafe