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The most common indicators of hypothyroidism, or an  Thyroid Support Review under-active thyroid, are: unexplained weight gain, moodiness, fatigue, constipation, sensitivity to cold temperatures, sudden clumsiness, fragile hair and nails, and many more. An under-active thyroid inhibits your life activities in numerous ways. Hypothyroidism occurs when the thyroid gland malfunctions, failing to produce sufficient amounts of thyroid hormones, specifically thyroxine (also spelled thyroxin.) Thyroxine determines how quickly nutrients are converted into energy and how efficiently food is burned within the body.

Normally, the thyroid gland makes four hormones: Thyroxine (T4), triiodothyronine (T3), diiodothyronine (T2) and monoiodothyronine (T1). The hormones contain iodine, and the numbers signify the number of iodine atoms in each hormone molecule. T3 is not made directly, but is produced from T4. Since T3 is a more efficient hormone than T4, this conversion is important. Because the hormones control the body's metabolic rate, their absence can affect every organ in the body. This can include general depression of many of the cellular systems and oxidation processes in the body, that are needed for energy production. The metabolic activities in the cells decrease. Metabolic wastes can then filtrate into the organs, causing them to become sluggish

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