According to the ChemAnalyst, “In the final quarter of 2023, the North American market for Dolutegravir Sodium experienced noticeable fluctuations in prices, indicating a consistent downward trend throughout the period. Dolutegravir Prices initially rose steadily at the beginning of the quarter but saw a significant decline by its conclusion.”

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The pricing of Dolutegravir, a crucial antiretroviral medication used in the treatment of HIV/AIDS, has been a subject of considerable debate and scrutiny. Originally developed by ViiV Healthcare, a subsidiary of GlaxoSmithKline, its cost has sparked controversy due to the stark differences in pricing between countries. While in high-income countries like the United States and those in Europe, Dolutegravir is often priced significantly higher, sometimes reaching hundreds of dollars for a month's supply, its cost is substantially lower in middle- and low-income countries where the burden of HIV/AIDS is often the highest. This stark contrast in pricing stems from various factors, including patent protection, negotiation power of governments and organizations, manufacturing costs, and differential pricing strategies employed by pharmaceutical companies. Despite efforts to make essential medications more affordable through initiatives like the Medicines Patent Pool and negotiations with generic manufacturers, the pricing of Dolutegravir remains a contentious issue, highlighting the ongoing challenges in ensuring equitable access to life-saving medications for all individuals affected by HIV/AIDS.