So, what does this have to do with coronary artery stenosis? As the heart becomes overworked due to coronary artery stenosis impeding oxygen delivery, the heart muscle begins to weaken. This weakening affects the coronary spongy tissue in the coronary artery. This spongy tissue provides the body with the materials it needs to construct new blood vessels and the nutrients required to keep the heart muscles healthy. If the coronary artery stenosis impeded all of the heart muscle's potential ability to work then coronary spongy tissue would die off resulting in death. Such scenario increases demand for fractional flow reserve, thereby aiding growth of the fractional flow reserve market.
High prevalence of myocardial ischemia is also expected to aid in growth of the fractional flow reserve market. Myocardial ischemia is the condition wherein the coronary vasculature fails to adequately provide for the heart's requirements. In myocardial ischemia, the walls of the coronary artery become too thick and/or too stiff. The results are decreased blood flow, less oxygen supply to the heart muscles, and decreased coronary sponginess which can lead to the buildup of plaque in the coronary arteries and ultimately, heart attack and/or stroke.
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