Melatonin is produced by a tiny gland in the human body known as the pineal gland. A pea-sized gland sits just above the brain’s centre. It helps your body figure out when to sleep and when to wake up.
Melatonin production is higher at night than during the day. The levels usually begin to increase when the sun sets in the evening. They fall when the sun rises in the morning. The amount of energy your body produces is influenced by the amount of light you receive each day as well as your biological clock.
Melatonin supplement come in a variety of forms, including tablets, liquids, and chewables. They come in both natural and synthetic varieties. Animals’ pineal glands are utilised to generate natural forms. A 10 mg melatonin pill can be used to protect oneself from a variety of illnesses.
Why Should You Take Melatonin?
Melatonin is a sleeping medication that is used by people who have trouble falling asleep and staying asleep. It’s also used to treat a variety of other sleep disorders. This might be linked to a sleep problem called delayed sleep phase disorder.
Melatonin, on the other hand, cannot be used to treat serious sleep problems including obstructive sleep apnea, narcolepsy, or chronic insomnia.
You might wish to try melatonin if you have a job that interrupts your sleep routine, provides you with odd working hours, longer than twelve hours causing you to face diseases such as sleep work disorder.
It is also good for curing or preventing jet lag for people who have to frequently cross borders for the purpose of work and have to spend long exhausting hours in an airplane. Some people feel tired and exhausted while travelling across time zones and Melatonin can help them get rid of their tiredness and feel a burst of energy in their bodies.
Melatonin has very strong antioxidant properties making it a great thing to be consumed on a regular basis. Traditional antioxidants like vitamins C and E only bind one free radical per molecule, whereas it binds up to 10. Melatonin has a high bioavailability, allowing it to pass across the blood-brain barrier as well as the placenta. Melatonin’s antioxidant properties are linked to increased superoxide dismutase, glutathione peroxidase, reductase, and catalase activity.
BENEFITS OF MELATONIN- CAN IT HELP WITH COVID 19?
The coronavirus disease (COVID-19) pandemic has quickly spread throughout the globe, impacting about 64.50 million people in 191 countries. Almost 1.49 million individuals have died as a result of the infection, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Covid 19 pandemic had a high death rate in the beginning that has caused people to stress upon the need of substances that can possibly prevent them from getting the disease or reduce the effects of the disease.
In their study, which was published in the journal Diseases, the researchers looked at the potential benefits of melatonin for COVID-19 patients, their improvement, responses of patients to melatonin as compared to other substances, and various other things. They looked at data that melatonin protects against SARS-CoV-2 infection, has anti-inflammatory, immunoregulatory, and antioxidant properties, counteracts chronodisruption, and fights a range of comorbidities like metabolic syndrome and diabetes.
Melatonin’s efficient binding and suppression of calmodulin, which governs the surface expression and retention of ACE2 in the plasma membrane, is another way it may regulate viral infection.
According to a team of researchers from the University of Toronto in Canada, melatonin can be utilised as an adjuvant to increase the efficacy of anti-SARS-CoV-2 vaccines. The studies conducted by these researchers were a groundbreaking success as they came to believe the drug might be a “silver bullet” in the fight against the COVID-19 outbreak.
The coronavirus causes pulmonary inflammation, which demands the activation of inflammasomes. Melatonin prevents these inflammasomes from working. Anxiety and a lack of sleep reduce overall immunity making the body of a person filled with tension, weak, unstable and sometimes in severe cases, makes the person unconscious. Melatonin improves sleep, reduces anxiety, and enhances immunity contributing to the physical as well as emotional well being of any person. Fibrosis may be the most serious side effect of COVID-19 that can damage various things and can result in long term problems for a person. Melatonin has been proven to aid in the prevention of fibrosis in the human body making it a great healer. Mechanical ventilation may be necessary, although it poses risks due to oxidative stress, which melatonin might reduce.
Thus we may instantly avoid the formation of severe coronavirus symptoms by using the safe, over-the-counter medicine melatonin in patients who are suffering with the novel coronavirus, lessen its symptoms or decrease coronavirus disease immunology in patients’ health after the active infection phase has ended. Melatonin has unparalleled benefits and slim to none side effects so it is a wiser option to consume melatonin to prevent oneself from coronavirus or to at least spare oneself from side effects.
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