There are two ways to make a pharmaceutical injection: liquid and dry. Lyophilized injections and dry injections are the two categories into which dry injections fall. The distinction between liquid injections and lyophilized injections is discussed in this blog. Let's start by discussing liquid injection.
- The liquid injection takes less time to process and handle.
- The medicine is liquid at this time.
- Reconstituting a liquid injection does not require the use of additional sterile diluent.
- When you manufacture a liquid injection, the manufacturing cost is significantly lower because the apparatus and equipment are less expensive.
- The production process is also easy.
- The injection of liquid is more susceptible to contamination. As a result, the stability and shelf life are lower.
- The handling and processing times for lyophilized injection are longer.
- The medication is in a solid state.
- You must use a more sterile diluent when reconstituting a lyophilized injection because it is solid.
- The lyophilized injection has a higher manufacturing cost since it needs specialized apparatus and equipment.
- The production process is labor-intensive and complicated.
- This injection is not susceptible to contamination because it is in solid form. It is more stable and has a longer shelf life than liquid injection.
There is a greater demand for lyophilized injection than for liquid injection. As a result, several businesses are Pharma Injection Manufacturers in India.
What advantages can lyophilized injections offer?
- Patients who are asleep and unable to swallow pills or capsules can benefit from these injections. It is a convenient and preferred solution for these patients.
- These injections can be used to treat patients who are unwilling to cooperate.
- Patients who don't respond to their prescribed medication are treated with lyophilized injections.
- All of these shots have 100% bioavailability. Why does that matter? It refers to how much and how quickly the circulatory system absorbs the medicine that has been supplied. According to studies, lyophilized injections are quickly absorbed. As a result, the body becomes prepared to react promptly to the medicine supplied.
- The first-pass effect is avoided. The first-pass effect is a phenomenon of drug metabolism in pharmacology. When a drug's concentration decreases before it reaches the patient's circulatory system, experiments demonstrate that when these injections are given, the first-pass effect is comfortably avoided.
Thus, lyophilized injections have a variety of advantages. Its widespread use is due to this. Compared to regular liquid injections, there has been a significant increase in its production. In comparison to liquid injections, lyophilized injections are significantly more in demand nowadays, and India is home to several pharmaceutical companies that produce them.