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Usually, that produces more side effects what's unique about cbd is despite all these mechanisms of action um almost none of those activities are bad for you um cbd is a remarkably benign drug um in terms of its side effect profile so this is all a good thing Buy Terpenes one other mechanism of action I should report is um cbd also inhibits fatty acid amino hydrolase which is the enzyme that breaks down anandamide an endocannabinoid in the brain and elsewhere so it may boost what we call endocannabinoid tone um the overall activity of the endocannabinoid system which is generally going to be a protective mechanism on keeping our physiology in balance so over time with this boosting of endocannabinoid tone it's generally going to be helpful in a large variety of disturbances diseases and so you mentioned also Marinol synthetic thc that's been around for a while but it hasn't really caught on it's not really used very much.


So what's going on there how does the synthetic thc compare to other forms of cannabis, okay well it is thc without everything else, and as I mentioned um pure thc is a lousy drug it doesn't make people happy it makes them dysphoric unhappy also people who take it feel very scattered hard to think hard to function it was proven effective in treating nausea associated with chemotherapy and was approved by True Terpenes the FDA cleared back in 1985. then in 1992, it was also approved for aids wasting associated with HIV but it's never been popular it's never been had an active uh following on the black market such that uh by 1999 it was rescheduled from schedule two to schedule three less restrictive because there wasn't uh evidence of its abuse um even people who are accustomed to cannabis who try Marinol uh tend to find it hard to handle and don't like it um.


So it's not often used in clinical medicine um right so basically it's thc without anything else it doesn't have benefit of cbd with it to allay side effects or terpenoids that contribute to the beneficial properties and also reduce the adverse event profile right interesting so pure thc is behaving differently presumably because it doesn't have these other compounds around that are interacting with it in some way people don't tolerate it as well and we know that there's a lot of other stuff in cannabis one more question before we go to the herbal side of things you mentioned that epidialex was i think 97 percent cbd so do we know what the other three percent is or at least whether or not the other three percent is efficacious with respect to its epilepsy treatment yeah i'm going to say probably not i mean there's just a trace of thc um fda remains a bit thc phobic at least on cannabis based medicines on there's probably a trace amount of other Terpenes for sale cannabinoids and terpenoids but it's pretty stripped down okay so we've got epidialex that's mostly cbd we've got sativex that's thc cbd we've touched on this idea that there are interactive effects between thc and cbd we've discussed marinol synthetic thc and how it doesn't behave the same as herbal you know plant-derived thc we've touched a little bit on some of the other minor cannabinoids can you start talking a little bit about this concept of the entourage effect and maybe let's let's actually back into it from the plant's point of view.

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