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The Oxycodone drug was first synthesized in Germany in 1916 from thebaine. It became available for use in the USA in 1939. Oxycodone is on the World Health Organization's List of Essential Medicines. Oxycodone is available as generic and brand-name medications such as Oxycontin and Oxaydo. In 2021, it was the most commonly prescribed painkiller medication in the United States of America, with more than 15 million prescriptions. For many years Oxycodone was used overseas as a component of combination short-acting analgesics, including NSAIDs and paracetamol.

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What side effects can Oxycodone cause?

Oxycodone can cause side effects. Tell the doctor if any of these symptoms are severe or don't go away:

  • drowsiness and flushing
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Some side effects can be severe like:

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  • loss of appetite, weakness, or dizziness
  • decreased sexual desire
  • inability to get or keep an erection
  • chest pain and hives
  • irregular menstruation
  • itching and rash
  • swelling of the lips, face, tongue, throat, eyes, feet, ankles, hands, or lower legs
  • difficulty breathing or swallowing
  • hoarseness, seizures, and lightheadedness when changing positions

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