Candy Swift

Candy Swift's articles

Introduction to Causes, Symptoms, and Treatments of Immunoglobulin A Deficiency

The most prevalent primary immunodeficiency is immunoglobulin A (IgA) deficiency, characterized by the presence of a low level of IgA in the bloodstream.  This disorder increases the possibility of mucous membrane infections in the ears, lungs, sinuses, as well as gastrointestinal tract. People who suffer IgA deficiency are more likely to develop some immunodeficiency diseases. And studies have shown the functions of […]

CRISPR Gene-Editing Pushes Forward Therapy for Novel Treatment for Chronic Pain

Recently, studies have proved that CRISPR-based gene silencing technology can alleviate chronic pain in mice. Although the therapy is still a long way from human use, scientists predict that it is a promising way to eliminate chronic pain that lasts for months or years. In 2018, the World Health Organization (WHO) included chronic pain as an independent […]

CAR-T Cell Therapy & Surgery for Solid Tumor Treatment: The Whole is Greater Than Sum of Parts

The past decade has witnessed ongoing progress in immune therapy to ameliorate human health. As an emerging technique, chimeric antigen receptor (CAR) T-cell therapy has the advantages of specific killing of cancer cells, a high remission rate of cancer-induced symptoms, rapid tumor eradication, and long-lasting tumor immunity, opening a new window for tumor treatment. CAR […]

AI for Pharma: First Antibody Drug Designed Using AI Is Writing A New Chapter

Artificial intelligence (AI) technology has beaten humans at games of chess and become famous globally. Now, AI and machine learning (ML) have revolutionized almost all types of industries. In a data-driven age where companies across all parallels of the industry are adopting big data and AI technologies, the pharmaceutical industry is no exception. Bimekizumab is the first-in-class monoclonal antibody, […]

Novel Findings on CAR-T Therapy Give Fresh Promise for Tumor Treatment

Chimeric antigen receptor T-cell (CAR-T) therapy is a novel cell immunotherapy technology that has been developing very rapidly in recent years. By the end of 2021, the U.S. Food and Drug Administration (FDA) had approved five CAR-T therapies, bringing hope to a number of patients. And research into CAR-T technology continues, with scientists from all […]

What Is Immunoglobulin A Deficiency?

The most prevalent primary immunodeficiency is immunoglobulin A (IgA) deficiency, characterized by the presence of a low level of IgA in the bloodstream.  This disorder increases the possibility of mucous membrane infections in the ears, lungs, sinuses, as well as gastrointestinal tract. People who suffer IgA deficiency are more likely to develop some immunodeficiency diseases. And studies have shown the functions of […]

Creative Biolabs Unveils GTOnco™ Immuno-oncology Assay Services at Immuno-Oncology Summit

Immuno-oncology (IO), emerging as a novel approach to taking advantage of the body's immune system to fight cancer, has been a game changer in cancer treatment research. With abundant drug development experience over the past years, Creative Biolabs is dedicated to offering a full range of IO therapy development services, and recently has introduced upgraded GTOnco™ immuno-oncology […]

Creative Biolabs Unveils GTOnco™ Immuno-oncology Assay Services at Immuno-Oncology Summit

Immuno-oncology (IO), emerging as a novel approach to taking advantage of the body's immune system to fight cancer, has been a game changer in cancer treatment research. With abundant drug development experience over the past years, Creative Biolabs is dedicated to offering a full range of IO therapy development services, and recently has introduced upgraded GTOnco™ immuno-oncology […]

An Introduction to Major and Minor Histocompatibility Antigens

On the surface of healthy cells, there are special molecules called major histocompatibility complex (MHC). They play a key role in presenting foreign antigens to immune cells, especially by activating T cells. They work for the adaptive immune system. Major histocompatibility molecules are present in almost all nucleated healthy cells of humans. Mature red blood cells […]

Top 5 Biotechnology Industry Trends in 2023

As biotechnology continues to innovate and develop, many innovative technologies have gradually made significant breakthroughs after years of accumulation and in-depth research, which are expected to further break through the barriers to the development of existing technologies and achieve wider and better applications of technologies. The following 5 strategies will continue to grow and develop […]

An Introduction to Intravenous Immunoglobulins and Natural Autoantibody

Human plasma is rich in a variety of antibodies including IgA, IgM, and IgG antibodies. Concentrated antibodies, known as intravenous immunoglobulins (IVIG), can be obtained from plasma by physical separation. IVIG contains a small amount of natural autoantibody. Natural autoantibody (NAA), is a seminal part of the immune system originating from B1-cells and is mainly of the IgM […]

CAR-macrophage: Powerful Immune Enhancer to Fight Cancer

Macrophages are common phagocytes in various mammalian tissues, which play many different roles in normal development, homeostasis, tissue repair and even immune response to pathogens. Their diversity means that they are involved in almost every human disease, and are also the main therapeutic target because their functions can be enhanced or inhibited to change the circumstances […]

An introduction to IgE Antibody: Key Player in Autoimmune Diseases

The prevalence of autoimmune diseases is about 7-9% and can be divided into organ-specific diseases, such as type I diabetes, multiple sclerosis, inflammatory bowel disease, myasthenia gravis, Hashimoto's disease, and autoimmune uveitis, and systemic diseases, including systemic lupus erythematosus, rheumatoid arthritis, mixed connective tissue disease, systemic sclerosis, and Sjogren's syndrome. The core of autoimmune diseases is […]

Journal Scientist Claims Alzheimer's Aβ*56 Theory a Fraud

On July 21, Science released an article titled “BLOTS ON A FIELD? A neuroscience image sleuth finds signs of fabrication in scores of Alzheimer’s articles, threatening a reigning theory of the disease“. Once this article was issued, scientists around the world who study Alzheimer's disease were stunned. In 1906, Alzheimer, a German neuropathologist, discovered special […]

Gene Editing Takes a Major Step Forward in Tackling Cardiovascular Disease

On July 13, 2022, a volunteer in New Zealand became the first patient in the world to undergo gene editing to lower “bad” cholesterol. According to an article in MIT Technology Review, this important development not only signals the future of using gene editing technology to prevent cardiovascular disease, the world's “biggest killer,” but also […]

New Research Directions: Antibody Cell Conjugates for Cancer Treatment

After the era of chemotherapy, targeted therapy, and immunotherapy, a new type, antibody-drug conjugates (ADCs), have opened the era of the fourth-stage drug therapy for oncology with remarkable success. Technological advances have also led to a collision of old and new concepts in conjugate drugs, resulting in the emergence of various novel methods. What are the […]

For Bispecific Antibody Community: Don’t Miss out on These Upcoming Events!

Bi-specific antibodies (BsAb) recognize and bind two different antigens or epitopes simultaneously and block two different signaling pathways to exert their effects. Compared with monoclonal Ab (mAb), which recognizes a single antigen, BsAb has many advantages. First, BsAb can redirect specific immune effector cells to adjacent tumor cells to enhance tumor killing, and BsAb can […]

The Battle Continues: Facing the Obstacles of Oncolytic Virotherapy Development

Immunotherapy has shown to be a potential treatment for a variety of cancers in recent decades. Oncolytic viruses (OVs) could well be designed to proliferate and lyse tumor tissues selectively while sparing normal non-neoplastic host cells and boosting antitumor immunity, providing a unique immunotherapeutic approach for cancer treatment. Given their possibility, OVs still have a number […]

Treatment on Leukemia Steps Forward with Novel Immunotherapy

Leukemia is a cancer of the blood or blood-forming cells and therefore sometimes referred to as blood cancer. While the exact cause of leukemia is not known, risk factors have been identified, including radiation exposure, certain chemotherapy for cancer, smoking, ,family history of leukemia, and exposure to certain chemicals such as benzene. Leukemia is generally classified […]

Bispecific Antibodies Could Be the Next Big Advance in Tumor Treatment Research

Monoclonal antibodies, tumor vaccines, immune checkpoint inhibitors, CAR-T cell immunotherapy, and bispecific antibodies are all effective cancer immunotherapy methods now available. CAR-T cells and bispecific antibodies, in particular, have gotten a lot of interest as potential anti-tumor immunotherapy techniques. Despite significant technical challenges in technology and industry, BsAb is seen as a promising medication for […]

First Complete Human Genome Sequence Published–New Beginning of Gene Therapy

Genetic sequences contain human genetic information, and we have never stopped deciphering our genetic information. On April 1, the first and most complete sequence of the human genome to date was published, and the relevant findings were published in papers in the journal Science. The complete sequencing and analysis work was performed by 114 scientists. These […]

New CAR-T Finding in April: Combination Therapy with Oncolytic Cells Improves Solid Tumors Treatment

Nowadays, cancer has been recognized as the prime enemy of human health. In the thousands of years of cancer-fighting history, human beings have never retreated from fighting with bare hands to evolving into a high-tech war on all fronts. Cell immunotherapies are part of the high-tech weapons to overcome cancer, which have overcome the challenges and […]

Cell Therapy Takes on Solid Tumors: World's First Bispecific TCR-T Therapy Receives FDA Approval

On January 26, 2022, the U.S. Food and Drug Administration (FDA) approved the marketing of Kimmtrak (Tebentafusp-tebn), an innovative therapy from a British biotechnology company, for the treatment of HLA-A*02:01-positive adult patients with unresectable or metastatic uveal melanoma (mUM). Notably, this is the first FDA-approved therapy for unresectable or metastatic mUM and the first FDA-approved T cell […]

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