gmittaldelveinsight

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Janus kinase (JAK) Inhibitors Competitive landscape report 2022 by DelveInsight

Janus kinase (JAK) Inhibitors pipeline constitutes 40+ key companies continuously working towards developing 45+ Janus kinase (JAK) Inhibitors treatment therapies, analyzes DelveInsight   Janus kinase (JAK) Inhibitors are the latest drug class of disease-modifying medication to emerge for the treatment of rheumatoid arthritis (RA). They are a small molecule-targeted treatment and are the first oral […]

PD-1 and PD-L1 Inhibitors pipeline constitutes 180+ key companies continuously working towards developing 200+ PD-1 and PD-L1 Inhibitors treatment therapies, an

Programmed Cell Death Protein 1 (PD-1) plays a vital role in inhibiting immune responses and promoting self-tolerance through modulating the activity of T-cells, activating apoptosis of antigen-specific T cells and inhibiting apoptosis of regulatory T cells. Programmed Cell Death Ligand 1 (PD-L1) is a trans-membrane protein that is considered to be a co-inhibitory factor of […]

Oncolytic Virus pipeline constitutes 150+ key companies continuously working towards developing 175+ Oncolytic Virus treatment therapies, analyzes DelveInsight

The oncolytic viruses (OVs) are organisms able to identify, infect, and lyse different cells in the tumor environment, aiming to stabilize and decrease the tumor progression. They can present a natural tropism to the cancer cells or be oriented genetically to identify specific targets. Several OVs are being studied as a potential treatment for cancer […]

Microbiome Competitive landscape Report 2022 by DelveInsight

Microbiome pipeline constitutes 130+ key companies continuously working towards developing 200+ Microbiome treatment therapies, analyzes DelveInsight Microbiome is the collection of all microbes, such as bacteria, fungi, viruses, and their genes, that naturally live on our bodies and inside us. Although microbes are so small that they require a microscope to see them, they contribute […]

Molecular Diagnostics (MDx) Market in the MENA Region

Introduction Molecular diagnostics (MDx) is the application of the molecular biology technique used in the study of human diseases, including infectious diseases, inherited conditions as well as cancer. The research focuses on genomic and proteomic analysis to identify the disease biomarkers, creating better diagnostics that ultimately find new treatments and potential cures. The techniques used […]

DelveInsight- Healthcare Consulting Services

To co-construct business transformation, DelveInsight assists clients through a multidimensional, purposeful, and credible market analysis that accelerates business growth and overcomes challenges via profound healthcare domain expertise with data-to-insights capabilities. DelveInsight has expertise in healthcare business consulting, with the ability to take a deep dive into business problems and emerge with actionable insights, enabling business […]

Unraveling the Potential of CRISPR Technology in the Gene-editing Space

CRISPR technology or CRISPR/Cas9 technology is a genome-editing tool derived from the bacterial defense system against viruses and plasmids. The system comprises the Cas9 nuclease enzyme to create site-directed dsDNA (double-stranded DNA) break and a guide RNA, which is a predesigned 20 bp long RNA sequence within a more extended RNA scaffold. This sequence guides […]

A CRISPR WAY TO USE STEM CELLS

Stem Cells therapies and CRISPR gene-editing are not new. Having able to grow the desired cells and manipulate the genome system have proved to be the most important breakthrough so far. We all are aware of the fact that Embryos possess the potential to produce pluripotent cells that researchers experiment on to produce Regenerative Medicine. But that results in the killing of […]

CRISPR proves to be a blessing for LASSA fever

The ability of CRISPR to change an organism’s DNA has lead researchers, particularly from Nigeria to use the tool to perform diagnostic tests. Since CRISPR therapeutics is all about targeting the genome-specific sequence, the test is believed to pinpoint the exact viral strain circulating. The recent epidemic of Lassa fever in Nigeria resulted in researchers to weigh the probability of using a diagnostic test based on gene editing tool CRISPR. The […]

Researchers say CRISPR edits to a human embryo worked

The researchers announced that they had edited human embryos to repair a damaged gene that can lead to heart failure, but critics raised their eyebrows. Now, new evidence confirms that the gene editing was successful, said by reproductive and developmental biologist Shoukhrat Mitalipov of Oregon Health & Science University in Portland, and colleagues report in “Nature” that all of the conclusions were basically […]

NgAgo gene-editing, claiming to be a better alternative to CRISPR gene editing, falls into a controversy in peer-reviewed papers

Six months ago, Chinese researchers reported that an enzyme called NgAgo could be used to edit mammalian genes – and that it might be more accurate and more versatile than the popular CRISPR-Cas9 gene-editing technique. But almost immediately, other scientists complained on internet forums that they could not replicate the experiment. Now, a paper with […]

The Curious Case of CRISPR Technology

  CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), a gene-editing technology, has set a record by reaching clinics from the research laboratory in a very short time, as NIH’s Recombinant DNA Advisory Committee has approved the first clinical trial of the technology in the U.S. for coming June. The trial investigators have proposed to exploit this technology […]

Evaluation of the Advancing Developmental and Epileptic Encephalopathy Treatment Pipeline

Developmental and Epileptic Encephalopathy (DEE) is a term used to describe a category of severe epilepsies that are marked by severe developmental delays or possibly the loss of developmental skills in addition to seizures that are frequently drug-resistant. Cognitive processes are significantly impacted by seizures, interictal epileptiform activity, and the neurobiological basis of epilepsy in […]

Chlamydia Treatment: Is it the End of the Antibiotic Era?

The most prevalent bacterial sexually transmitted infection worldwide is chlamydia. Infections with Chlamydia are asymptomatic in 50–88% of men and women, and 46% of infections spontaneously disappear after a year. Men can get epididymitis and epididymo-orchitis from persistent chlamydia infection, while women can develop pelvic inflammatory illness, ectopic pregnancy, and tubal infertility. Chlamydia infection can […]

Obesity: A Worldwide Pandemic with Advancing Management Options

Obesity is a chronic health problem that causes the body to accumulate abnormally large amounts of fat or adipose tissue, which is dangerous for one's health. Between calories consumed and calories expended, there is an imbalance. Heredity, a sedentary lifestyle, excessive fat, sugar consumption (energy-dense meals), certain drugs, and endocrine problems are the reasons for […]

Competitive Intelligence: Stay Ahead of the Competitors in 2022 !!

Competitive intelligence tools can help analyze data and produce insightful analyses that can be used to find R&D synergies between partner companies, comprehend operational metrics that are common to both parties, or assess the risks associated with any kind of agreement.   Improved Research and Development: By keeping track of industry failures, pharmaceutical competitive intelligence […]

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