A different user or process is now accessing the file, as indicated by the message QuickBooks Company File in Use. To fix, make sure everyone has logged off, shut down QuickBooks, and then restart the machine. If the problem continues, try repairing the file with QuickBooks File Doctor or get in touch with support. Do you require assistance with QuickBooks? For immediate assistance, call 1.855.856.0042 to speak with our Experts Team.