The Amniotic Membran is made up of both tissue and cells, and when applied to a wound as a biological dressing, it promotes the formation of new soft tissue. The amnion's stromal and epithelial layers include biologically active cells that secrete cytokines and growth factors with anti-inflammatory, anti-bacterial, anti-immunogenic, and anti-fibrotic properties.
In order to replace skin, human placental membranes were first employed in the early 1900s. The chorionic and Amniotic Membrans were involved in these procedures. When De Rotth advised using the Amniotic Membrane alone to heal an ocular burn wound, it became the first time it was done so in ophthalmology. After a successful course of treatment, Amniotic Membran usage fell out of favour until better processing and storage methods were created in the early 1990s. Visit the Parent's Guide to Cord Blood Foundation at to learn more about cord blood banking.
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