The endocannabinoid system or ECS is a system that comprises of cannabinoid receptors and endocannabinoids. It plays a crucial role in maintaining balance or homeostasis without which it becomes very difficult for the human body to function. The ECS is also responsible for maintaining many other functions in the human body including fertility.
The entourage effect gained traction in 2011 when Russo published an article in the British Journal of Pharmacology examining the potential interactions between THC and various cannabinoids and #trueterpenes.
The ECS consists of two receptors namely CB1 and CB2 that interact with the incoming cannabinoids. While CB1 receptors are present in the nervous system and the brain, CB2 receptors are present in the remaining parts of the body. Both the receptors are responsible to handle several functions including immunity among other things.
What’s fascinating is how THC and CBD react with these receptors. THC, in particular, fits very well with these receptors and activates several functions in the body.
