Let’s answer the actual internet question first: can you take losartan potassium at night?
In many cases, yes. Cozaar’s patient instructions basically say: take it exactly as prescribed, take it with or without food, and if you miss a dose, just take the next one at your regular time—which strongly implies the time of day is flexible, as long as you’re consistent.
So why do some people prefer bedtime? One very unglamorous reason: dizziness can happen, especially early on or if your blood pressure drops more than expected.
Some guidance even suggests taking the first dose before bed if it makes you feel dizzy—because it’s easier to be dizzy while horizontal than while trying to act normal in daylight.
Now, the chrono-nerd corner: you may see posts claiming nighttime dosing is better for blood pressure because of circadian rhythms. There is research on bedtime vs morning dosing, but the evidence isn’t one-size-fits-all, and some reviews warn that evening dosing could be problematic for certain people (e.g., those prone to low nighttime BP). Translation: don’t switch your timing just because the internet yelled night mode! —it’s worth checking with a clinician if you’re changing your routine.
Cozaar is the odd ARB out because it can lower uric acid.
Multiple reviews conclude that losartan is the only ARB that consistently shows a meaningful reduction in serum uric acid, likely because it increases uric acid excretion (a uricosuric effect).
This doesn’t magically turn it into a gout medication—but it’s a real “bonus skill” that’s unusual in its drug family, and it’s been studied even in higher-risk groups like people with diabetes and kidney disease.
Tiny safety footnote (because blood pressure meds are not Skittles): Cozaar can cause low blood pressure symptoms like dizziness, and it’s important to follow your prescriber’s instructions—especially if you have kidney issues, take potassium supplements/salt substitutes, or use NSAIDs often.
