NGS library prep market growth challenges and trends

The NGS Library Preparation Market is expected to reach $6.47 billion by 2030 at a CAGR of 16% from 2023 to 2030. The typical NGS workflow involves several steps, including sample pre-processing, library preparation, sequencing, and bioinformatics. Library preparation is a crucial step in NGS workflow and involves preparing DNA or RNA samples to be compatible with a sequencer. It includes processes such as nucleic acid fragmentation, adapter ligation, and library quantitation. Numerous vendors offer a variety of NGS library preparation solutions for NGS analysis.

The growth of this market is driven by the declining costs of sequencing, the increasing prevalence of cancer and genetic disorders, the growing utilization of NGS in disease diagnostics and precision medicine, and rising R&D investments and healthcare expenditures. In addition, the increasing applications of next-generation sequencing technology and collaborations between vendors to develop automated library preparation protocols are expected to provide significant market growth opportunities.

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NGS Library Preparation Market: Future Outlook

The NGS library preparation market is segmented by product, application, sequencing type, end user, and geography. The study also evaluates industry competitors and analyzes the country and regional-level markets.

Based on product, in 2023, the reagents & consumables segment is expected to account for the largest share of the NGS library preparation market. The large market share of this segment is attributed to factors such as the increasing demand for library preparation kits and reagents, the high number of research activities, and the numerous applications of NGS in different fields, such as drug and biomarker discovery and diagnostics.

Based on application, in 2023, the research & other applications segment is expected to account for the largest share of the NGS library preparation market. The large market share of this segment is attributed to the increasing demand for gene-based medicines, growing investments in drug research and development activities, and increasing research programs for personalized medicine.

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Based on sequencing type, in 2023, the targeted sequencing segment is expected to account for the largest share of the NGS library preparation market. The large market share of this segment is attributed to the benefits offered by targeted sequencing, such as low cost, fast turnaround time, and accurate and easy interpretation of targeted sequencing results in the study of disease-related genes.

Based on end user, in 2023, the pharmaceutical & biotechnology companies segment is expected to account for the largest share of the NGS library preparation market. The large market share of this segment is attributed to the rising pharmaceutical R&D expenditures, the growing demand for new drug discoveries & development, and the increased utilization of NGS technology for biomarker discovery.

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Geographic Review

In 2023, North America is expected to account for the largest share of the NGS library preparation market, followed by Europe and Asia-Pacific. North America’s major market is attributed to the factors such as governments’ increased support and investments to enhance genome sequencing infrastructure in the region, the increasing R&D investments by pharmaceutical and biopharmaceutical companies, and the presence of key market players in the region.

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Key Players

The key players operating in the NGS library preparation market are Illumina, Inc. (U.S.), Thermo Fisher Scientific Inc. (U.S.), QIAGEN N.V. (Germany), Agilent Technologies, Inc. (U.S.), Danaher Corporation (U.S.), Pacific Biosciences of California, Inc. (U.S.), PerkinElmer Inc. (U.S.), F. Hoffmann-La Roche AG (Switzerland), New England Biolabs, Inc. (U.S.), Tecan Group Ltd. (Switzerland), Merck KGaA (Germany), Diagenode S.A. (Belgium) (Subsidiary of Hologic, Inc. (U.S.)), and Beijing Genomics Institute (BGI) (China).

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Scope of the Report:

NGS Library Preparation Market, by Product

Reagents & Consumables
- DNA Library Preparation
- RNA Library Preparation
Instruments & Workstations

NGS Library Preparation Market, by Application

Research and Other Applications
- Drug Discovery
- Agriculture & Animal Research
- Other Applications
  (Note: Other applications include basic research (genomics, molecular biology, and other life sciences), and forensics & food microbiology.)
Clinical Application
- Reproductive Health
- Oncology
- Infectious Disease
- Other Clinical Applications
  (Note: Other clinical applications include applications in detection aberrations in neurological disorders, rare diseases, metabolic and immune disorders, and food-borne illnesses.)

NGS Library Preparation Market, by Sequencing Type

Targeted Genome Sequencing
Whole Genome Sequencing
Whole Exome Sequencing
Other Sequencing Types
(Note: Other Sequencing types include degradome sequencing, chromatin immunoprecipitation (ChIP) sequencing, and methylation sequencing)

NGS Library Preparation Market, by End User

Pharmaceutical & Biotechnology Companies
Hospitals & Diagnostic Laboratories
Academic Institutes & Research Centres
Others End Users
(Note: Other end users include forensic laboratories & security agencies, the food industry, and the agriculture industry)

NGS Library Preparation Market, by Geography