BUFFER SALTS (FOR BIOLOGICAL)

avt pharma May 14, 2025

8 min read

Buffer salts (for Biological) belong to biological buffer systems, which contain dozens of varieties like buffered electrolyte salts,Tris and HEPES.

Buffered electrolyte salts are a type of buffer salt that can help maintain the ionic balance of biological systems. The advantages of buffered electrolyte salts including high purity, low impurities, production in accordance with GMP guideline, stable supply and high cost-effective.

Tris is a buffered salt widely used in the field of biomedicine. Buffered Salt is a combination mineral supplement that may be helpful in reducing tiredness. AVT has newly launched tromethamine (TRIS), which is in the process of NMPA and US FDA registration.

HEPES, short for 2-(4-(2-hydroxyethyl)-1-piperazinyl)-ethanesulfonic acid, is another commonly used buffer salt known for its ability to maintain pH at physiological levels. Both Tris and HEPES are widely used in research and industries such as biotechnology and pharmaceuticals.

TYPES OF BUFFERED SALT (FOR BIOLOGICAL)

TRIS (for injection)

Tromethamine Tris: 1. English name: Tris Base; 2. Chemical name: Tris(hydroxymethyl)aminomethane; 3. Trade name: Tris; 4. Molecular formula: C4H11NO3; 5. CAS: 77-86-1; 6. Grade: chemical reagent grade; 7. Properties: This product is white crystal; 8. Purity: >99% (see COA for details); 9. Solubility: water 550 g/L (25℃); 10. Molecular weight: 121.14; 11. Melting point: 167-172℃; 12. Boiling point: 219-220℃ 10 mm Hg.

TRIS-HCL (for injection)

Trometamol hydrochloride (Tris-HCl) is used in many applications within molecular biology laboratories as a buffering agent. It is also extensively employed in the preparation of antibody drugs, nucleic acid drugs, and vaccines.

HEPES (for injection)

As a zwitterionic sulfonic acid buffering agent, HEPES exhibits excellent buffering capacity within the pH range of 6.8 to 8.2 and can maintain a stable pH for an extended period. It is widely utilize...

Sucrose Octasulfate Potassium (for injection)

Sucrose Octasulfate Potassium (K-SOS) is a novel excipient. It is used as the raw material for the preparation of Triethylammonium Sucrose Octasulfate salt (TEA-SOS) used in liposome formation.The exc...

TRIS (pharmaceutical grade)

Tris (CAS number: 77-86-1, white crystalline) is a buffer salt widely used in the field of biomedicine. Its full name is Tris (hydroxymethyl) aminomethane. pKa at 25°C is 8.06. Commonly used in prote...

Tris-HCl (pharmaceutical grade)

Tris-HCl is a widely utilized buffering agent in the biopharmaceutical industry, playing a crucial role in keeping the pH of a solution stable. As a mixture of tromethamine (Tris) and hydrochloric aci...

HEPES (pharmaceutical grade)

The molecular formula of HEPES is C8H18N2O4S. Its structure contains both an acidic sulfonic acid group (-SO3H) and two basic tertiary amine nitrogens, so it is amphoteric and can be used to prepare zwitterionic buffers. The buffer solution generally consists of a certain amount of HEPES dissolved in distilled water, and then sodium hydroxide is used to adjust the pH to an appropriate value. Its pH buffer range is generally 6.8~8.2.

TRIS (reagent grade)

Tris (CAS number: 77-86-1, white crystalline) is a buffered salt supplement widely used in the field of biomedicine. Its full name is Tris (hydroxymethyl) aminomethane. pKa at 25°C is 8.06. Commonly used in prote...

TRIS-HCL (reagent grade)

HEPES (reagent grade)

SOS-TEA(aq)

Chemical name: N,N-diethylethanamine;[(2R,3R,4S,5R,6R)-2-[(2S,3S,4R,5R)-3,4-disulfooxy-2,5-bis(sulfooxymethyl)oxolan-2-yl]oxy-3,5-disulfooxy-6-(sulfooxymethyl)oxan-4-yl] hydrogen sulfate Molecular for...

BUFFERED SALT (FOR BIOLOGICAL) EFFECTS

Tromethamine (Tris) is a buffer salt widely used in the field of biomedicine. Chemical formula is C4H11NO3. It is white crystalline particles, commonly used in protein or nucleic acid buffers. The effective range is usually between pH 7.0-9.2.

Tris is used for the growth of protein crystals under different pH conditions. Tris is also one of the main components of protein electrophoresis buffer. It forms a buffer system with glycine in the electrophoresis buffer to stabilize the pH during electrophoresis.

In addition, Tris is also an intermediate in the preparation of surfactants, vulcanization accelerators and some drugs. Titration standard substance is also its usage.

How do Buffer Salts (for Biological) Work?

1. The basicity of Tris base is strong, so we can use only this buffer system to prepare buffers with a wide range of pH ranging from acidic to basic. The application range is wide.

2. Tris buffer has little interference with biochemical processes and does not precipitate with calcium, magnesium ions and heavy metal ions.

3. Tris is highly soluble in water and is inert to many enzyme reactions.

4. Tris has high buffering capacity, especially between pH 7.5-9.0.

5. Tris buffer is widely used and plays an important role in biochemistry, molecular biology, in vitro diagnosis, cosmetics, coatings and other fields.

Buffered Electrolyte Salts Play a Vital Role in Drug Development

We are committed to providing pharmaceutical companies with the best solutions to ensure drug stability and patient safety. We use advanced production technology to ensure that each batch of buffered electrolyte salts has high purity and consistency to meet strict drug development standards. Our buffer salts are GMP and ISO certified to ensure quality and safety, and are suitable for a variety of pharmaceutical formulations and biotechnology applications. We provide detailed quality reports and traceability information to ensure that every production step is transparent and traceable. Choosing our buffered salts, you will get high-quality, reliable and traceable products to help your drug development projects succeed.

As a pharma excipients company, we can provide kinds of pharmaceutical excipients for sale, anything you need, please contact us.

BUFFER SALTS (FOR BIOLOGICAL)