Get a Cell Line Authentication DNA Test in India

Authenticating cells of interest is an integral part of many genetic and other biological experiments, research, etc. It is the process of identifying the cells used for the experiment. In this process, the cell line under observation has to be cross-matched with the reference cell line. Cell Line Authentication DNA Test in India is frequently used in fields like medicine, vaccine development, genetics, cell biology, and many more. For the same purposes, human cell lines or mouse cell lines are used wherever necessary.

The Need for Cell Line Authentication Testing

Cells provide structure and support to the human body. Using the right cell for the experiment is very important for the researchers to complete their research and get the desirable results. However, for some reason, they may not get valid outcomes..

Misidentification: The cell lines, in this case, are misidentified at the source. This indicates that the incorrect cell line was acquired during the collection process.Cross contamination: There are a number of different cell lines being stored and handled continuously at research labs. Cross-contamination is a common problem there. This happens due to the mix-up of one cell type with the other one. Moreover, the contamination of the tested cell lines with environmental pollutants is a common occurrence at such facilities.Genetic Drift: It is among the most common types of errors. Due to different factors like heat, humidity, and others, the DNA of the cells may undergo change. In such cases, the cell loses its original identity. Such an error is called a ‘genetic drift.’

In case cell line authentication tests are not performed on the cells of interest, the researchers may end up getting the wrong results. This can be a serious issue, not just for their career but for the related sectors as well. The easy availability of accurate Cell Line Authentication DNA tests in India can help individuals with their research, study, etc.

Methodology Behind a Cell Line Authentication DNA Test in India

It depends on short tandem repeats (STRs) on the DNA. STRs are the repeating and non-coding sequences on the DNA strand and are located throughout the human genome.

 Here are the steps involved in this test:

Collection of samples (cell line of interest)Extraction of DNA from the cellsDNA analysis by using STR’sPolymerase chain reaction amplifies the STRsCapillary electrophoresis yields a DNA profile.Comparing the resultant DNA profile with the database.Find the cell line match and use the match formulation method to check for cross-contamination.Find out the misidentified cell line.

Where Should One Go for Cell Line Authentication DNA Test in India?

DNA Forensics Laboratory Pvt. Ltd. (DFL) is among the most trusted companies to use standardized techniques for Cell Line Authentication. They provide NABL-accredited DNA testing services around India and the globe.

DNA Forensics Laboratory Pvt. Ltd. has worked with many Medical Institutes, such as,

AIIMS (All India Institute of Medical Science)Bhabha Atomic Research InstituteIIT Kanpur and IIIM Jammu

They provide Cell Line Authentication to different private organizations in India; here are some:

BT Sciences ServicesCDRI, LucknowIGIB, DelhiNational Brain Institute, ManesarNational Institute of Cancer Prevention and Research NoidaNational Centre for Cell Science, Pune, etc.

Moreover, they have 400+ collection centers across India, and one can visit the closest collection center to provide a DNA sample. The commitment to quality and expertise has made DNA Forensics Laboratory Pvt. Ltd. the most preferred choice for researchers and scientists.