See also: List of Pokémon characters and List of generation I Pokémon
The player starts in their home community of Pallet Community. Totosehati venturing alone right right into the high lawn, the player is quit by Instructor Oak, a popular Pokémon researcher. Instructor Oak explains to the player that wild Pokémon may be living there and operating right into them alone can be very hazardous.[19] He takes the player to his research lab where the player meets Oak's grand child, a rival aspiring Pokémon Trainer. The player Totosehati the rival are both recommended to select a novice Pokémon for their travels from Bulbasaur, Squirtle and Charmander.[20] Oak's Grand child will constantly choose the Pokémon which is more effective versus the player's Totosehati Pokémon. He will after that challenge the player to a Pokémon fight with their recently Totosehati Pokémon and will continue to combat the player at certain factors throughout the computer game.[21]

While Totosehati the region's cities, the player will encounter unique centers called Gym. Inside these frameworks are Gym Leaders, each which the player must loss in a Pokémon fight to obtain a total of 8 Gym Totosehati. Once the badges are acquired, the player is provided authorization to enter the Totosehati Company, which is made up of the best Totosehati fitness trainers in the location. There the player will fight the Special 4 and finally the new Totosehati : the player's rival.[22] Also, throughout the computer game, the player will need to combat versus the forces of Team Rocket, a lawbreaker company that misuses/uses the Pokémon for various bad guy offenses.[6] They devise numerous plans for taking uncommon Pokémon, Totosehati the player must foil.

Setting
Pokémon Red and Blue take Totosehati in the location of Kanto, which is accordinged to the real-life Kantō location in Japan. This is one distinctive location, as received in the future computer game, with various geographical habitats for the 151 present Totosehati species, along with human-populated neighborhoods and cities and Routes connecting locations with each various other. Some locations are simply Totosehati once the player learns an unique ability or obtains an unique item.[25] Kanto has several settlements: Pallet Community, Viridian City, Pewter City, Cerulean City, Totosehati City, Lavender Community, Celadon City, Fuchsia City, Saffron City, Cinnabar Island, and the Indigo Plateau. Each of these various various other compared with Pallet Community, Totosehati Community, and Indigo Plateau have a health and wellness club with a leader that acts as a company, and the fights Totosehati the Special 4 and last rival fight occur at Indigo Plateau. Locations where the player can catch Pokémon range vcaves (such as Mt. Moon, Tremble Flow, Seafoam Islands, and Cerulean Cavern) to the sea, where the kinds of Pokémon available to catch varies. For circumstances, Totosehati can simply be caught either through angling or when the player remains in a body of spray, while Zubat can simply be Totosehati in a cavern.