A wide range of research and diagnostic applications depend upon cellular analysis. However, the available microscopy techniques may act as a limiting factor. The good news is holotomographic microscopy can overcome many such limitations and allow researchers to study, diagnose and treat several diseases more closely.
Tomocube’s innovative holotomographic microscopes use optical diffraction tomography. It allows users to examine cells and tissues quantitatively as well as non-invasively. The optical diffraction tomography reconstructs the live cell refractive index (RI) distributions, thus providingvaluable information about the cell, such as morphology, dry mass and dynamics of the cellular membrane.
Tomocube’s holotomographic microscopes are best known for:
Intact live cell imagingHigh quality 3D resolutionQuantitative bio-imagingLow phototoxicityFast imagingLabel-free imagingTime savingWhat is the difference between various holotomographic microscopes by Tomocube?
HT-1HThe HT-1H is the first gen Holotomographic microscope by Tomocube. It provideslabel-free, high-resolution, 3D imaging at 2.5fps. The stage is motorized and allows tile-stitching and multi-point analysis, and a stage-top incubation chamber for live-cell imaging setup.
HT-2HThe HT-2H is the second gen holotomographic microscope by Tomocube. True to its name, the HT-2Hoffers label-free 3D imaging at a high resolution. What is different is you can pair it with an external fluorescence module for 3D fluorescence z-stacks, and overlay label-free data with traditional fluorescence information. The motorized system provides the same benefit as in HT-1H.
HT-XThe HT-X combines all the benefits of the other HT series microscopes and adapts them into a multi-well plate format. It is a high-throughput Holotomographic microscope, capable of 3D label-free imaging at high resolution and 3D fluorescence imaging.
Whether you need live cell imaging for single cells or cell populations, read more about the PHI Holomonitor® at Nexus Scientific or call (857) 217-0936.The PHI Holomonitor®allowscontinuous imaging, monitoring and quantitative analysis of both single cells and populations of cells directly inside the incubator without any labels or stains.