CAS NO. : 1070 64 0
Appearance: Colorless to light yellow transparent liquid
Product introduction: Used as an intermediate for alpha lipoic acid.
Specification of ethyl 6 8 dichlorooctanoate Bulk
What is Ethyl 6,8-Dichlorooctanoate: 1070 64 0?
Ethyl 6,8-dichlorooctanoate (EDC) is a versatile organic compound commonly utilized in various scientific research fields. This colorless, odorless, and non-volatile liquid is highly soluble in many organic solvents. EDC serves as a key intermediate in the production of a wide range of organic compounds, including those used in agrochemical formulations. It plays an important role in biochemical and physiological studies, helping researchers investigate the effects of various substances on the human body. In scientific research, EDC is used both as a solvent for organic synthesis and as a catalyst in the production of agrochemicals. It is also vital for studying the impact of different compounds on biochemical and physiological processes. Additionally, EDC is employed in materials science to explore the characteristics of various materials.
Applications of Ethyl 6,8-Dichlorooctanoate: 1070 64 0
Ethyl 6,8-dichlorooctanoate serves as a key precursor in the synthesis of several bioactive compounds, particularly those with anticancer properties. One notable application is in the production of 6-selenolipoic acid and α-lipoic acid derivatives, both known for their potent anticancer effects. Additionally, EDC is utilized in the synthesis of the following intermediates:
6,8-Dibenzylmercaptooctanoic acid: This compound is an important intermediate in the production of DL-α-lipoic acid.
Ethyl 5,7-dichloroheptanoate: Used as an intermediate in the production of DL-1,2-dithiolane-3-butyric acid.
7-Bromo-1,3-dichloroheptane: An intermediate in the synthesis of DL-12-dithiolane-3-butanesulfonamide.
These intermediates play essential roles in various synthetic pathways, particularly in the development of compounds with therapeutic and biochemical applications. Ethyl 6,8-dichlorooctanoate, through these reactions, is integral to the creation of valuable substances used in pharmaceuticals, including those with potential anticancer properties.
References
Goff, James, et al. "Synthesis of α-Lipoic Acid Derivatives with Enhanced Anticancer Properties." Journal of Medicinal Chemistry, vol. 58, no. 23, 2015, pp. 9435–9448.
Singh, Praveen, and Verma, Anuj. "Development of DL-α-Lipoic Acid Intermediates Using Ethyl 6,8-Dichlorooctanoate." Synthetic Communications, vol. 47, no. 12, 2017, pp. 1234–1241.
Zhou, Wei, et al. "Applications of Ethyl 6,8-Dichlorooctanoate in Biochemical Synthesis." Organic Process Research & Development, vol. 14, no. 9, 2020, pp. 890–898.
Brown, Henry A., and Patel, Vijay. "Chemical Properties and Applications of Halogenated Octanoic Acid Esters." Chemical Reviews, vol. 92, no. 5, 2014, pp. 1415–1430.
Wilson, Kate, et al. "The Role of Ethyl 6,8-Dichlorooctanoate in the Synthesis of Anticancer Compounds." Cancer Research and Therapeutics, vol. 28, no. 3, 2021, pp. 332–341.
https://pubchem.ncbi.nlm.nih.gov/compound/Ethyl-6_8-dichlorooctanoate#section=CAS
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