Protein A Resin Is A Type Of Chromatographic Medium That Is Commonly Used For The Purification Of Monoclonal Antibodies

Sushil Mahalle
Sushil Mahalle
1 min read

Protein resin is a widely used chromatography medium for purification of monoclonal antibodies (mAbs). It is a type of affinity chromatography resin that specifically binds to the Fc region of immunoglobulins, such as IgG, and separates them from other components of a sample. Protein resin has several benefits that make it an attractive option for mAb purification.

 

One of the main benefits of Protein A Resin is its high binding capacity. It can bind up to 100 mg of IgG per milliliter of resin, which is significantly higher than other chromatography media. This high binding capacity means that Protein resin can process large amounts of starting material, resulting in higher yields of purified mAbs.

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https://blogger-aware.blogspot.com/2023/03/protein-resins-is-act-procedure-made.html

 

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