1-Methyladenosine

1-Methyladenosine (Synonyms: 1-methyl Ado, NSC 92165)

Catalog No.GC33463

A modified nucleoside and biomarker

Products are for research use only. Not for human use. We do not sell to patients.

Description

1 methyladenosine is an RNA modification originating essentially from two different reaction types, one catalyzed by enzymes and the other the result of the reaction of RNA with certain alkylating agents.

[1]. Hauenschild R, et al. The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent. Nucleic Acids Res. 2015 Nov 16;43(20):9950-64.

Chemical Properties

Chemical Properties

Cas No.

15763-06-1

SDF

Synonyms

1-methyl Ado, NSC 92165

Canonical SMILES

OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN(C)C3=N)O1)O)O

Formula

C11H15N5O4

M.Wt

281.27

Solubility

DMSO : 150 mg/mL, Water : 28.1mg/mL

Storage

Store at -20°C

General tips

Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.

To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.

Shipping Condition

Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.