2-Ketoglutaric acid

2-Ketoglutaric acid (Synonyms: α-KGA, NSC 17391, 2-Oxoglutaric Acid)

Catalog No.GC30136

An intermediate in the citric acid cycle

Products are for research use only. Not for human use. We do not sell to patients.

Description

2 ketoglutaric acid is an intermediate compound of the Krebs cycle and is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.

[1]. Rocchiccioli F, et al. Microdetermination of 2-ketoglutaric acid in plasma and cerebrospinal fluid by capillary gas chromatography mass spectrometry; application to pediatrics. Biomed Mass Spectrom. 1984 Jan;11(1):24-8.

Description

2-Ketoglutaric acid is an intermediate compound of the Krebs cycle and is also connected to glutamic acid and glutamine metabolisms through the transamination reactions.

[1]. Rocchiccioli F, et al. Microdetermination of 2-ketoglutaric acid in plasma and cerebrospinal fluid by capillary gas chromatography mass spectrometry; application to pediatrics. Biomed Mass Spectrom. 1984 Jan;11(1):24-8.

[2]. 

Chemical Properties

Cas No.

328-50-7

SDF

Synonyms

α-KGA, NSC 17391, 2-Oxoglutaric Acid

Canonical SMILES

OC(=O)CCC(=O)C(O)=O

Formula

C5H6O5

M.Wt

146.1

Solubility

Water : 50 mg/mL (342.23 mM)

Storage

Store at -20°C

General tips

Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.

To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.

Shipping Condition

Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.