The DNA synthesize market has experienced significant growth in the recent years, owing to increased adoption of DNA synthesizers in gene synthesis applications. DNA synthesizers are used to produce both short and long strands of customized DNA through solid-phase phosphoramidite chemical synthesis techniques. Ability of DNA synthesizers to synthesize DNA sequences from scratch has enabled advancements in research and production of therapeutic genes and oligonucleotides. DNA synthesizers offer high specificity and reliability compared to traditional gene synthesis methods. Rising demand for DNA synthesis technologies in molecular diagnostics, genomics, and development of new therapies is a major factor fueling investments in DNA synthesizers globally. The Global DNA Synthesizer Market is estimated to be valued at US$ 4.3 Bn in 2024 and is expected to exhibit a 20 % CAGR over the forecast period 2023 to 2030.
Key Takeaways
Key players operating in the DNA Synthesizer market are Thermo Fisher Scientific, Merck KGaA, Agilent Technologies, Danaher Corporation (Integrated DNA Technologies), GenScript Biotech Corporation, Eurofins Genomics, LGC Limited, BioAutomation Corporation, Bio-Rad Laboratories, Twist Bioscience Corporation, Hamilton Company, New England Biolabs, Nippon Genetics, LGC Biosearch Technologies, DNA Script, Ribbon Biolabs GmbH, and Camena Bioscience. Thermo Fisher Scientific dominates the global DNA synthesizer market with a market share of over 30% and has a strong geographical presence through its Oligo and Gene synthesis business.
The global demand for DNA synthesizers is growing rapidly due to increasing adoption of DNA synthesis techniques in molecular diagnostics, discovery research, and advancement of genome editing technologies. DNA synthesizers are increasingly being used to produce synthetic genes, gene fragments, siRNAs, shRNAs, DNA primers, oligonucleotides and more. Rising research in areas of synthetic biology, cancer genomics and agriculture biotechnology is propelling market growth.
Geographical expansion of key DNA synthesizer manufacturers across regions such as North America, Europe, Asia Pacific and South America is another factor contributing to growth of the global market. Manufacturers are enhancing their global distribution networks and establishing manufacturing facilities in emerging countries to gain higher market share. Increasing collaborations between academic research institutions and DNA synthesizer providers is also expected to support market expansion over the forecast period.
Market drivers
Increasing R&D investments in genomics and biotechnology: Growing investments by governments and private organizations in genomics research, drug discovery and precision medicine is one of the key drivers of the DNA synthesizer market. Synthesized DNA is finding increasing use as research models, biomarkers and targets in genomics research. Advancements in genome engineering techniques relying on gene synthesis is further fueling demand.
Development of new gene and vector synthesis applications: Emerging applications of gene synthesis such as development of gene and vector therapeutics, manufacture of oligonucleotides and molecular tools are propelling growth of DNA synthesizer market. Manufacturers are developing new synthesis chemistries, throughput methods and software to enhance utility in these applications. Need for shorter turnaround times and lower costs in application development is driving automation and scalability of DNA synthesizers.
Growing synthetic biology market: Expansion of global synthetic biology market that relies on use of synthesized DNA as foundational blocks is a major growth driver. Rising tools development, workforce expansion and investments are accelerating application scope of synthetic biology, thus supporting DNA synthesizer adoption. Development of CRISPR-Cas9 technology requiring customized DNA and RNA oligos is positively impacting DNA synthesizer sales.
Impact of geopolitical situation on DNA Synthesizer Market growth and future strategies
The current geopolitical tensions have impacted the DNA Synthesizer Market in multiple ways. Supply chain disruptions caused due to the Russia-Ukraine conflict have created delays and increased the costs of raw materials procurement for market players. Transport restrictions implemented between certain countries have also posed challenges in seamless movement of finished products. Furthermore, heightened political risks and economic uncertainties prevailing across some major markets have reduced expenditure on research activities utilizing DNA synthesis technologies by academic institutions and biotech firms.
To cope with these difficulties in the short-run, manufacturers are focusing on developing alternative regional sources for key components and exploring new logistics routes. In the long-run, building flexible manufacturing footprints spanning multiple geographic clusters would help mitigate regional supply chain dependencies. Forming strategic alliances with local players in emerging economies represents another route to circumvent geopolitical barriers and tap into high-potential growth areas. Additionally, intensifying R&D efforts to introduce more automated and affordable benchtop DNA synthesizers can aid wider adoption even during times of constrained research funding.
Geographical regions with high concentration in DNA Synthesizer Market
North America has historically been the dominant regional market for DNA synthesizers, accounting for over 40% of the global revenue. Presence of a large number of well-established life sciences and biopharma companies engaged in advanced research & development activities has sustained the high demand. Additionally, considerable investments by governments and private entities in synthetic biology and genomics domain have propelled the regional market. Europe is another major revenue generating region, supported by presence of various global industry leaders and a robust academic research infrastructure. Continuous technological improvements by domestic players also contribute to its prominent position.
Fastest growing region in the DNA Synthesizer Market
The Asia Pacific region is poised to witness the fastest expansion in the DNA Synthesizer Market over the coming years. This growth can be attributed to increasing R&D expenditures by pharmaceutical companies to accelerate drug discovery initiatives relying on DNA synthesis. Establishment of global research centers by leading organizations and expanding involvement of domestic players are amplifying regional demand. Additionally, growing focus of governments to strengthen synthetic biology and healthcare research through investments and initiatives offers a promising outlook. China, India and other Southeast Asian countries stand to gain significantly owing to their large population base and growing biotechnology industry.
