alexbrowns

 United States, New York
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities and metabolites, APIs, natural compounds, ADCs, stem cell molecule and chiral compounds. Details about Details about fermentation CDMO service https://bio-fermen.bocsci.com

alexbrowns's articles

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Coumarin Synthesis Building Blocks with Anticancer Activity

Coumarin, also known as bisfuran cyclooxaphthalone, is a lactone compound widely found in Rutaceae and Umbelliferae. Coumarin is a general term for a class of natural products with a benzo-αpyrone structure, which is widely used in medicine, fragrance, dyes, instrument analysis, agriculture and other fields. The drug molecules with coumarin and its derivatives as the basic […]

Technical Development Trend of ADC Drug

Antibody-drug conjugate (ADC) is a humanized or human monoclonal antibody conjugated to highly cytotoxic small molecules (payloads) through a chemical linker. It is a novel form of treatment with great potential to make a paradigm shift in cancer chemotherapy. Compared with traditional chemotherapy, this new antibody-based molecular platform can selectively deliver effective cytotoxic payloads to target […]
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Fermentation Production of ADC Payloads

Targeted therapies have significantly advanced the field of cancer therapy, and among these, antibody-drug conjugates (ADCs) have emerged as a viable therapeutic strategy. ADCs increase efficacy and decrease systemic toxicity by fusing the potency of cytotoxic drugs with the specificity of monoclonal antibodies (mAbs). The manufacture of high-quality and stable payloads by fermentation techniques is […]

Liposomes for Flavor and Fragrance Encapsulation

IntroductionFlavors are generally divided into natural flavors and artificial flavors, of which natural flavors are widely used, but natural flavors have low bioavailability, poor absorption, rapid metabolism, poor stability, easy oxidation, irritability, and other problems. In general, such problems can be solved by microencapsulation of flavors. Such microencapsulation is usually accomplished using water-soluble polymers co-adsorbed […]
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BOC Sciences Ensures Secure and Rapid Delivery of Isotopically Labeled Materials for Drug Compound Development

“Whether clients require an internal standard for quantitative analysis in a clinical study, need to determine metabolic routes and rates, or desire an assay substrate molecule that releases a labeled product distinct from the endogenous product molecules present in a cell or tissue sample, BOC Sciences is ready to advise and offer strategic solutions,” the […]
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The Development Process of DUBTAC

The use of Proteolysis Targeting Chimeras (PROTACs) to degrade dysfunctional proteins has shown great potential to target proteins that were previously considered “undruggable”, and several projects have entered clinical evaluation worldwide. Aberrant protein degradation, in fact, is also a pathogenic mechanism in some diseases, such as cystic fibrosis (CF) and some forms of cancer. Therefore, for these […]
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Fermentation CDMO Service for Cosmetic Industry

BOC Sciences has comprehensive R&D platforms and supporting functions, as well as the GMP complied quality system and over 20 years of experience in microbial pharmaceutical development. We provide Fermentation CMO Service to world-wide partners in big pharma, biotech and biopharma company, with solutions for the development and biomanufacturing of a broad range of biological […]