siran's articles Enhancing Drug Activity and Maximizing Therapeutic Effects: A Comprehensive Approach In the realm of pharmacy, researchers have long grappled with the central challenge of maintaining drug potency and optimizing therapeutic outcomes. The journey from drug administration to the realization of its efficacy is an intricate process, divided into three distinct phases: the pharmaceutical phase, the pharmacokinetic phase, and the pharmacodynamic phase. Only by ensuring an […] July 17, 2023July 17, 2023 Saving Bookmark this article Bookmarked Excited States in Quantum Chemistry: Insights from ZINDO, CIS, and TDDFT The electrons in atoms, ions, or molecules generally occupy multiple energy levels due to the influence of the electric field of the nucleus. When electrons are in the lowest energy level, they are in the ground state, while at higher energy levels, they transition to the excited state. As electrons move from the ground state […] July 17, 2023July 17, 2023 Saving Bookmark this article Bookmarked Decoding the Language of Proteins: Insights from Molecular Dynamics Simulation Molecular dynamics simulation is a powerful and widely employed computational method that investigates the motion and interactions of molecules under different conditions, revealing the structure, dynamics, and physical-chemical properties of molecules. This article aims to delve into the fundamental principles, applications, and key techniques of molecular dynamics simulation, providing you with a better understanding of […] July 17, 2023July 17, 2023 Saving Bookmark this article Bookmarked What Are Potentials in Molecular Dynamics Simulation? Introduction The atoms in biomolecules are always in constant motion, and the functions of molecules and the interactions between them are closely related to the dynamics of the molecules involved. In other words, to understand the working mechanism of proteins or other biomolecules, molecular biologists must first be able to clearly know the movement patterns […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked Three Methods for Virtual Screening Various calculations are encompassed in the basic experiments related to drug discovery and preparation, such as the calculation of excited state, charge density, molecular volume and so on. One of the vital and extensively applied computing technologies is virtual screening, which is abbreviated as VS. By utilizing this technology, researchers can search the library of […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked The Key Factor of Excellent Drug Efficacy: Chemical Structure of Drug How to keep the drug active and give full play to its therapeutic effect has always been the primary problem to be solved by researchers in the field of pharmacy. It is a very complex process from drug administration to the generation of drug efficacy. Scientists have divided this process into three phases: Pharmaceutical phase, […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked How to Calculate the Excited State Due to the bondage of the electric field of the nucleus, electrons in atoms, ions, or molecules generally have many different energy levels. When at the lowest possible energy level, the electrons in these molecules are in the ground state, and when at a higher energy level, these electrons are transferred to the excited state. […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked Answers to Frequently Asked Questions Regarding Gene Ontology and GO Enrichment Analysis “Big data”, “omics”, and “data mining” are vocabulary we have often heard in recent years, and second-generation sequencing is often used in scientific research. No matter which sequencing company performs sequencing or data analysis, a standard analysis method will be seen in the final report: functional enrichment analysis. Given that most people know little about […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked The Key to Successful Experiment: Enzymatic Catalysis For scientists and researchers, in order to realize the design and development of new products such as drugs, the first step is to ensure the success of their experiments. Therefore, every chemical reaction in the experiment is of vital importance, and it only takes one wrong move to end in a total defeat. However, the […] May 30, 2021May 30, 2021 Saving Bookmark this article Bookmarked
Enhancing Drug Activity and Maximizing Therapeutic Effects: A Comprehensive Approach In the realm of pharmacy, researchers have long grappled with the central challenge of maintaining drug potency and optimizing therapeutic outcomes. The journey from drug administration to the realization of its efficacy is an intricate process, divided into three distinct phases: the pharmaceutical phase, the pharmacokinetic phase, and the pharmacodynamic phase. Only by ensuring an […] July 17, 2023July 17, 2023 Saving Bookmark this article Bookmarked
Excited States in Quantum Chemistry: Insights from ZINDO, CIS, and TDDFT The electrons in atoms, ions, or molecules generally occupy multiple energy levels due to the influence of the electric field of the nucleus. When electrons are in the lowest energy level, they are in the ground state, while at higher energy levels, they transition to the excited state. As electrons move from the ground state […] July 17, 2023July 17, 2023 Saving Bookmark this article Bookmarked
Decoding the Language of Proteins: Insights from Molecular Dynamics Simulation Molecular dynamics simulation is a powerful and widely employed computational method that investigates the motion and interactions of molecules under different conditions, revealing the structure, dynamics, and physical-chemical properties of molecules. This article aims to delve into the fundamental principles, applications, and key techniques of molecular dynamics simulation, providing you with a better understanding of […] July 17, 2023July 17, 2023 Saving Bookmark this article Bookmarked
What Are Potentials in Molecular Dynamics Simulation? Introduction The atoms in biomolecules are always in constant motion, and the functions of molecules and the interactions between them are closely related to the dynamics of the molecules involved. In other words, to understand the working mechanism of proteins or other biomolecules, molecular biologists must first be able to clearly know the movement patterns […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked
Three Methods for Virtual Screening Various calculations are encompassed in the basic experiments related to drug discovery and preparation, such as the calculation of excited state, charge density, molecular volume and so on. One of the vital and extensively applied computing technologies is virtual screening, which is abbreviated as VS. By utilizing this technology, researchers can search the library of […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked
The Key Factor of Excellent Drug Efficacy: Chemical Structure of Drug How to keep the drug active and give full play to its therapeutic effect has always been the primary problem to be solved by researchers in the field of pharmacy. It is a very complex process from drug administration to the generation of drug efficacy. Scientists have divided this process into three phases: Pharmaceutical phase, […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked
How to Calculate the Excited State Due to the bondage of the electric field of the nucleus, electrons in atoms, ions, or molecules generally have many different energy levels. When at the lowest possible energy level, the electrons in these molecules are in the ground state, and when at a higher energy level, these electrons are transferred to the excited state. […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked
Answers to Frequently Asked Questions Regarding Gene Ontology and GO Enrichment Analysis “Big data”, “omics”, and “data mining” are vocabulary we have often heard in recent years, and second-generation sequencing is often used in scientific research. No matter which sequencing company performs sequencing or data analysis, a standard analysis method will be seen in the final report: functional enrichment analysis. Given that most people know little about […] August 5, 2021August 5, 2021 Saving Bookmark this article Bookmarked
The Key to Successful Experiment: Enzymatic Catalysis For scientists and researchers, in order to realize the design and development of new products such as drugs, the first step is to ensure the success of their experiments. Therefore, every chemical reaction in the experiment is of vital importance, and it only takes one wrong move to end in a total defeat. However, the […] May 30, 2021May 30, 2021 Saving Bookmark this article Bookmarked
