centrabiohub's articles

A snapshot of the present clinical research landscape.   Healthcare and diagnostics research has gained momentum in the past century, with researchers worldwide striving to discover new and cost-effective clinical trial methods without compromising quality. With growing competition among pharmaceutical companies, there is a pressing need to increase the volume of clinical research and trials. […]
Peripheral Blood Mononuclear Cells (PBMCs) are a group of blood cells such as lymphocytes (T-cells, B-cells and NK cells), monocytes, and dendritic cells that play an essential role in modulating immunity in humans. It is also known as agranulocytes. PBMCs defend the body against cancer and other human pathogenic diseases and infections. How are Peripheral […]
Today, human tissue banking offers a wide range of opportunities and is essential to contemporary medical research. The specialized, licensed facilities known as tissue banks gather, process, store, and distribute human tissues for clinical transplantation, medical research, and educational purposes. Tissue banking is an idea that is as old as skin grafting itself. Typically, human […]
A biobank is a specialised facility that gathers, preserves and distributes priceless human biospecimens with associated data for clinical and experimental research. It also goes by the name “biorepositories.”  It is two types based on ownership and governance ie, public biobanks and commercial biobanks. Public biobanks own by governmental biomedical research organisations, universities or non-profitable […]
The COVID-19 pandemic affected nearly every aspect of the lives of people worldwide. Caused by a virus outbreak in December 2019, the coronavirus SARS-CoV-2 has since then posed a significant threat to global health. Due to the rapid development and distribution of COVID-19 vaccines, this devastating disease could fortunately be stopped resulting in the end […]
What are human biospecimens? Human biospecimens are crucial in research as they provide valuable biological material that can be used to study disease processes, test new treatments and diagnostic methods, and advance our understanding of human health and disease. It includes blood, tissue, urine, saliva, and other bodily fluids, and they can be collected from […]
Disease incidence and prevalence have reached unprecedented heights in today's fast-changing world, driving up the demand for cutting-edge medical research to develop the next generation of treatments and diagnostics for better disease management. Any medical discovery begins with human biosamples collected from patients. To advance studies and accomplish study targets, researchers must gather compatible human […]
Hashimoto's thyroiditis, also known as chronic autoimmune thyroiditis, is a persistent autoimmune disorder that affects the normal functioning of the thyroid gland. It is caused by the abnormal immunological processes known as cell- or antibody-mediated destroy the healthy cells of the thyroid gland, resulting in increased fibrosis and a decrease in the synthesis and release […]
What is Influenza? Influenza, or “the Flu,” is a common seasonal infection caused by RNA viruses from the Orthomyxoviridae family. There are four types of flu-causing viruses called influenza viruses: A, B, C, and D. Influenza A and B have been associated with severe epidemics with severe influenza symptoms. In contrast, influenza C causes milder […]
Central BioHub is one of the largest human biospecimen marketplaces, offering a fast and efficient process that saves researchers time and effort to spot desired research samples. Using our user-friendly online marketplace, scientists worldwide can acquire clinical research specimens banked in different human biospecimens biobanks and biorepositories within minutes.  Founded in 2017, Central BioHub was […]
Sexually transmitted diseases (STDs) are infections spread through sexual contact with an infected partner during vaginal, anal, or oral sex. According to the World Health Organization (WHO), over a million people are newly infected with STDs daily. However, most individuals do not show symptoms and remain undiagnosed during the early stages of infection. This has […]
Respiratory tract infections (RTIs) are a significant health issue affecting millions worldwide. They are the primary cause of hospital admissions, ICU stays, and premature death. But what are RTIs exactly? These infections are a group of airway infections caused by bacteria, viruses, and fungi. The respiratory tract includes parts involved in breathing, such as the […]
Before delving into the management of human biospecimens in research, it's essential to define what these specimens are. Human biospecimens, also known as human biomaterials or human biological samples, originating from the human body, such as blood, urine, sputum, faeces, saliva, organs, teeth, hair, tissues, DNA, bones, and other materials. These biological specimens are collected […]
The landscape of human biospecimen search In today's world, the incidence and prevalence of diseases have reached an unprecedented level, highlighting the need for advanced medical research to develop next-generation treatments and diagnostics for better disease management. The starting point for any medical discovery is human biospecimens obtained from patients. Researchers must collect matching human […]
High blood cholesterol is now regarded as the disease of the new millennium. Millions of people worldwide struggle with high cholesterol. But what does the term “high cholesterol disease” really mean? Let's examine this situation closely.  Hyperlipidaemia, a chronic disease condition marked by high blood cholesterol levels, is brought on by an overabundance of lipids […]
Sepsis, a life-threatening condition caused by the body's overwhelming response to an infection, poses a significant global health threat with millions of deaths annually. Despite substantial progress, managing sepsis remains challenging for healthcare professionals. However, biomedical research has shown promising advancements that could result in better outcomes and reduced mortality rates. Early detection of sepsis […]
Formalin-fixed paraffin-embedded (FFPE) human tissue samples had been a useful resource in biomedical research for decades dating back to 1893. They are readily available from clinical archives and provide precious insights into various diseases and their progression. Characterized by their ability to preserve tissue architecture and cellular morphology, human tissue samples support researchers worldwide in […]
What is biospecimen biobanking? Biobanking is the process of collecting, storing, and managing biological samples, such as tissues, blood, urine, and DNA, for use in scientific research. The samples are typically collected from patients and healthy donors to preserve their integrity and ensure their long-term viability at specialised facilities known as Biobanks. Today, biobanks play […]
Understanding Thyroid Diseases Thyroid disease is a group of medical condition affecting the thyroid gland's function, one of the most common endocrine disorders globally. The thyroid gland produces and secretes thyroid hormones (T3 and T4) into the bloodstream, which regulates essential body functions like metabolism, growth, and development. Any imbalance in thyroid hormone synthesis and […]
The uniqueness of genetic makeup of every human necessitates strengthening of translational and precision medicine research on human cells. Such research is crucial to identifying personalized treatments for various human diseases. Cytology, also known as human cell biology or human cell research, is the branch of science that involves studying and experimenting on human cells. […]
The American Association for Clinical Chemistry (AACC) is an international scientific organization of healthcare professionals dedicated to clinical laboratory science and its role in healthcare. The AACC provides a platform for laboratory professionals like clinical chemists, pathologists, researchers, and other healthcare professionals to them networking opportunities for collaborations, knowledge exchange, and advancing the field of […]


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