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Endemic infectious diseases are widespread in tropical and subtropical regions and are a major cause of morbidity and mortality. Tropical diseases are caused by multiple pathogens such as viruses, bacteria, and parasites which are transmitted by mosquitoes, ticks, and flies. Chikungunya, Dengue fever, and West Nile virus are examples of such endemic infectious diseases in the tropics.

The (sub-)tropical climate, with warm temperatures and high humidity, creates an ideal environment for the proliferation of pathogens. The diseases cause a variety of symptoms including fever, joint pain, fatigue, and skin rash. In severe cases, tropical diseases can lead to organ failure or even cause death. Tropical diseases can have long-lasting effects on individuals.

Diagnosis of Chikungunya, Dengue, and West Nile virus is typically performed with antibody-based assays and rapid-diagnostic tests. Furthermore, molecular tests, such as polymerase chain reaction (PCR) are utilized to identify the presence of viral genetic material. These tools enable accurate diagnoses of tropical diseases. Early diagnosis and rapid treatment are crucial to minimize the impact of these diseases.

Vaccines are the best tool to fight vector-borne diseases and typically target high-risk individuals. A dengue vaccine has been successfully established and is approved in several countries. Whilst vaccine candidates for chikungunya are currently evaluated in clinical trials, research is still needed to develop and test vaccines that stimulate immune responses against the West Nile Virus. Continued research efforts aim to enhance our understanding of chikungunya, dengue, and West Nile virus and develop more effective diagnostics, treatment, and prevention measures.

As a pioneer in tropical infection research programs, Central BioHub presents a wide variety of human serum and plasma samples collected from tropical disease patients. Our sample data is well-annotated and includes the clinical profile, medical history, as well as demographic information of donors. The search functions of Central BioHub are specifically designed to enhance your search results. We provide a variety of search options that will enable you to find just the right match. Explore our 550 tropical disease samples and revolutionize research on tropical diseases now:




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