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The level of AMH in the blood tends to decrease with age in parallel with the number of follicles, unlike other pituitary hormones (FSH and Inhibin B). As such, the anti-Mullerian hormone is considered to be the best reflection of the ovarian reserve. In addition, AMH is a good indicator of the success rate of certain protocols for ART and of possible risks of ovarian hyperstimulation. Indeed, there is a correlation between the AMH level (high) and the number of oocytes punctured after ovarian stimulation. Finally, even if its evaluation is not recommended for diagnostic purposes (no threshold value established), the level of anti-Mullerian hormone can be, when it is high, an indicator of polycystic ovary syndrome (PCOS). This increase is explained in particular by the increased number of small follicles growing in patients with this syndrome.

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