bocsciences

bocsciences's articles

  1. Biotech

Polymer Characterization — BOC Sciences

Polymer testing and characterization is a key to solving the relationship between material composition, structure, and performance. Through a series of characterization techniques, the size, morphology, structure, chemical composition, thermal properties, mechanical properties, etc. of polymers can be studied qualitatively and quantitatively. This is a complex and multi-faceted process that should only be done by those with years […]
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  1. Biotech

Insecticides and Metabolite Standards

Introduction to Insecticides   Insecticides are a class of chemicals mainly used to control agricultural pests and urban sanitation pests. The use of insecticides has a long history, a large amount and a variety of varieties, which have played an extremely important role in increasing agricultural production.   1. Classification of Insecticides Source According to the source […]
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  1. Biotech

Embracing Innovation–BOC Sciences Strengthens the Production of Cosmetics Ingredients

It's verified by BOC Sciences officials that the critical specialty chemical distearyl phthalic acid amide is now in steady supply, aiming to accelerate the development of cosmetics industry.   As a science-driven chemical manufacturer, BOC Sciences has been sticking to its path of innovation since its inception. Over the decades, its product portfolio has expanded to […]
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  1. Health

Therapeutic siRNA: Recent Advances and Prospects

The concept of RNA interference (RNAi) was raised in 1998 and is a naturally occurring defense mechanism against exogenous nucleic acid invasion and control of gene expression. Soon thereafter, small interfering RNAs (siRNAs) were identified as mediators of RNAi in mammalian cells. Then, siRNA delivery was found to be necessary and sufficient to induce RNAi-mediated […]
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  1. Biotech

Computer-Aided Drug Discovery Added to BOC Sciences Chemical Solutions

BOC Sciences helps clinicians and researchers to exploit the immense potential of Computer-Aided Drug Discovery in the design and identification of drug molecules and thereby helping the management of fatal diseases.   The recent outbreak of the deadly coronavirus disease 19 (COVID-19) pandemic poses serious health concerns around the world. The lack of approved drugs or vaccines […]
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  1. Biotech

BOC Sciences: Peptides Open New Path toward Osteoporosis Treatment

BOC Sciences declares that some of its peptide products have been proven applicable for osteoporosis treatment, which is a significant contribution to the therapeutic areas.   Bone tissue engineering and the research surrounding peptides have expanded significantly over the last few decades. Several peptides have been shown to support and stimulate the bone healing response and […]
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  1. Biotech

BOC Sciences Makes Easy Access to Polymerization Tech

Owing to the continuously upgraded synthesis technologies and analytical abilities, BOC Sciences has performed well in the polymer industry, serving the community with a comprehensive product portfolio and valuable technical support.   BOC Sciences thoroughly understands the significance of polymers in the chemical industry. Therefore, it has invested much energy in developing polymerization expertise, namely […]
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  1. Biotech

BOC Sciences: ADC Analysis and Characterization Support Development, Registration, and Release

BOC Sciences announces support for antibody–drug conjugate (ADC) development, registration, and release by providing comprehensive analysis and characterization technologies.   The development of antibody–drug conjugates (ADCs) poses challenges to bioanalysis because of their inherently intricate structures and potential for very complex catabolism. BOC Sciences, the leading ADC solution provider, proposes its integrated testing strategies for structure, purity, and […]
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  1. Biotech

BOC Sciences Rolled Out PEG GMP Manufacture Services for Broad Applications

BOC Sciences recently launched the PEG GMP manufacture service, a novel solution that aims at providing GMP-grade PEG products for a wide scope of applications.   After a long period of preparation, BOC Sciences eventually introduced its PEG GMP manufacture platform to the public in August, indicating its ability to flexibly produce high-purity PEG materials for various needs, either […]
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  1. Biotech

BOC Sciences Reports Its Antibody Modification and Conjugation Technologies in Detail

The chief technician of BOC Sciences ADC development center recently reported some detailed information regarding its antibody modification and conjugation technologies, bringing the audience and customers a better understanding of how BOC Sciences has contributed to the ADC industry.   The newest report on ADC tech released by BOC Sciences officials has attracted much attention from […]
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  1. Biotech

BOC Sciences Honored To Assist in the Antibody Research With High-Quality Chemicals

BOC Sciences' chemical products have been applied in a wide range of research projects and helped achieve groundbreaking breakthroughs.   Whether or not maternal vertically transferred antibodies can protect newborns against internally-replicating pathogens has remained a key unanswered question. Now, a new article Pregnancy enables antibody protection against intracellular infection published in Nature sheds light on this query.   The […]
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  1. Biotech

BOC Sciences Declares the Availability of 10,000 Impurities, All in Stock!

BOC Sciences recently confirmed to its customers that over 10,000 impurities are now in stock, ready for immediate delivery.   Since pharmaceutical impurities may increase the potential for toxicity, side effects, and serious implications for human health, the study on it is so much focused that there is a soaring demand for different types of impurity products. BOC […]
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  1. Biotech

BOC Sciences Outlines Its Contribution of Peptides to Cardiovascular Research

BOC Sciences' monthly report released in August showed that its peptide products had vastly facilitated the R&D of cardiovascular therapies.   February is set as American Heart Month since heart disease is the number one cause of death for most groups, affecting all ages, genders, and races. More than 600,000 Americans die from heart disease every […]
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  1. Biotech

BOC Sciences August Promotion: Comprehensive Labeled Peptides with Stable Quality

As a pioneer in stable isotopic labeling chemistry, BOC Sciences develops a large variety of SIL compounds. Its promotion of labeled peptides, the increasingly used materials for convenient detection in research, is on the boil in August.     BOC Sciences has produced hundreds of custom labeled peptides with stable isotopes of 2H (deuterium), 15N, and 13C. They are widely […]
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  1. Biotech

BOC Sciences August Promotion: Compound Docking Solutions for Drug Discovery

As the leading expert in computer-aided drug discovery, BOC Sciences has developed compound docking technologies to facilitate the discovery of novel ligands for over 30 targets.   Has compound docking ever brought us medicine? This was generally questioned in the pharmaceutical industry. With many innovators like BOC Sciences springing up and improvements being made in computational chemistry, compound docking is […]
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  1. Biotech

BOC Sciences 2022 Free Webinar: Viral RNA Modifications and Implications for Novel Therapeutics

BOC Sciences grandly announced the schedule of a free webinar on September 19th, 2022, at 11:00 EDT, which is a laudable event centering on the hot spot of RNA research during the pandemic.   BOC Sciences is an expert in RNA technologies. It is now renowned as the largest manufacturer of pseudoUridine and its derivatives, […]
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  1. Biotech

Effects of Endocytosis on the Receptor Targeting Mechanism of ADC Drugs

ADC is a complex that conjugates cytotoxic small molecule drugs to monoclonal antibodies through a rationally constructed linker, which can selectively deliver effective cytotoxic drugs into tumors. Currently, the FDA has approved 11 ADC drugs for marketing, and hundreds more are in clinical trials.   No. ADC Drugs Targets 1 Trastuzumab emtansine (T-DMI) HER2 2 […]
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  1. Biotech

Precision Fermentation for the Alternative Protein Industry

What is Precision Fermentation   Precision fermentation is a technology that utilizes microorganisms as cell factories to produce specific functional components. It allows microorganisms to be programmed to afford complex organic molecules, such as proteins, enzymes, fats, vitamins, natural pigments, etc. In biology, fermentations refer to specific metabolic pathways that extract energy from molecules, usually in the absence […]
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  1. Biotech

Peptides for Diabetes Research—a Special Offer of BOC Sciences

  BOC Sciences has been constantly enriching its peptide product library for years. Its peptides for diabetes research are recently brought into focus due to the growing concerns on this problem.   According to data from the WHO, a large number of adults are having diabetes mellitus, a chronic metabolic disorder characterized by hyperglycemia. The absolute […]
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  1. Biotech

Stable and Quality Supply of Phosphoramidites Is a Reality at BOC Sciences

As an expert in chemistry, BOC Sciences understands how important the quality of phosphoramidite is to successful oligo synthesis and remarkably, it has taken concrete actions to manufacture certified products.   Hundreds of phosphoramidites for oligonucleotide synthesis, not only the common DNA and RNA phosphoramidites but also 2′-modified phosphoramidites, reverse phosphoramidites, 3′-NH phosphoramidites, etc., are now within the range of BOC […]
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  1. Biotech

BOC Sciences Shares Its Strategic Emphasis on NTPs during the Pandemic

“Whether your studies involve DNA sequencing, cDNA synthesis, RT-PCR, RCA, MDA, DNA labeling, in vitro transcription, siRNA synthesis, or RNA amplification, we stock hundreds of modified or natural NTPs to suit your various molecular biological applications,” a BOC Sciences manager announces to the public.   As an active participant in the biotech and pharmaceutical industry, BOC Sciences emphasizes its […]
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  1. Biotech

Application review of pseudoUridine and its derivatives

Pseudouridine is the most abundant RNA modification in cellular RNA. Pseudouridine (abbreviated by the Greek letter psi- Ψ) is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic bond. The C-C bond gives it more rotational freedom and conformational flexibility. It has an additional […]
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  1. Biotech

mRNA Vaccines and PseudoUridine

1. AbstractThe field of mRNA vaccines has rapidly developed during the pandemic. In order to reduce the immunogenicity of mRNA vaccines, the introduction of naturally modified nucleotides was used. PseudoUridine is the most abundant modified nucleoside in RNA, also known as the “fifth nucleoside.” The introduction of pseudoUridine or N1-methylpseudoUridine into mRNA can effectively reduce […]
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  1. Science / Technology

Vital Solutions to Support COVID-19 Research

Many research institutes and pharmaceutical companies are now actively engaged in COVID-19 research and treatment development, which makes some supportive reagents, services, and consultations in high demand around the world.   This article briefly summarizes several relatively important solutions that can greatly facilitate COVID-19 research.   COVID-19 mRNA Vaccine Development Support The global outbreak of […]
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  1. Science / Technology

Key Elements for Efficient Fermentation Process Optimization in Pharmaceutical Industry

For large- or small-scale fermentation, process optimization in some critical steps plays an important role in improving efficiency because it can directly affect the formation, concentration, and yield of a particular fermentation end product, thus affecting the overall economics.   However, the improvement of fermentation process is frequently associated with a lot of challenges: it's expensive, laborious, open-ended, and time-consuming. There […]
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  1. Science / Technology

An Overview of PseudoUridine Modification in RNAs

It is an efficient way to regulate molecular function by applying specific chemical modifications on biological molecules. This article highlights the current heated pseudoUridine modification in RNA, which suggests new possibilities for novel drug or vaccine discovery.   An Introduction to PseudoUridines PseudoUridine (Ψ) is a post-transcriptional RNA modification that alters RNA-RNA and RNA-protein interactions and affects gene expression. PseudoUridine modification is also […]
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  1. Science / Technology

An Overview of Mainstream Carbohydrates in the Market

As one of the primary biomolecules in nature, carbohydrates are critical elements in nutrition provision, energy transportation, cell composition, etc. In view of their universality and essentiality in research, this article is an exploration of carbohydrates, especially those hot ones in the market.   Chemical Classifications of Carbohydrates There are different ways to classify carbohydrates, such as by formulae or by structures. And the […]
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  1. Biotech

Innovative Impurity Isolation and Identification Techniques at BOC Sciences to Address Pharmaceutical Impurity Issues

New York, United States—June 30, 2022—BOC Sciences announced impurity isolation and identification services using traditional and innovative impurity techniques.   “We’re happy to have achieved consensus with global pharmaceuticals to deal with the NDMA risk and other impurity concerns. We will continue to provide full support taking advantage of our rich experience and expertise,” stated the […]
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  1. Science / Technology

How to Optimize Fermentation Process? Learn from the Workflows of BOC Sciences

From the early stage of strain cultivation to final commercial production, the fermentation production process will go through a complicated set of workflows that require constant optimization. BOC Sciences, working with a group of versatile experts in microbiology, chemistry, and biology, has accumulated much experience in this field.   BOC Sciences divides the whole fermentation […]
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  1. Science / Technology

A Brief Guide to Identify a Reliable Supplier of Phosphoramidites

Synthetic DNA/RNA is an important technique in therapeutic DNA/RNA research, which is the undisputed truth in the pharma industry. However, if you interview a certain number of researchers specializing in DNA/RNA related fields, they would give the feedback that looking for the desired DNA/RNA synthesis materials and identifying a supplier worthy of long-term cooperation would […]
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  1. Science / Technology

A New Phase of BOC Sciences Partnership Expansion Unlocked after TIDES USA 2022

As the grand hybrid event TIDES USA 2022 is drawing to a close, BOC Sciences is reviewing its gains there, particularly many instructive thoughts and comments collected from global researchers. The in-person event TIDES USA 2022: Oligonucleotide & Peptide Therapeutics Conference was successfully concluded on May 12th, while the digital session is still ongoing. BOC Sciences dispatched […]
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  1. Biotech

Antibody-drug Conjugates Manufacturing and Future Focus

Antibody-drug conjugates (ADCs) are formed by covalent biochemical conjugation of monoclonal antibodies (mAb) with payload drugs through small molecular linkers. They are regarded as an emerging class of drugs designed for high-specificity targeting and destruction of cancer cells, since the specificity of mAb to tumor cells allows small-molecule drugs to target tumor tissues, effectively reducing […]
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  1. Biotech

Peptides Labeling with Stable Isotope

Peptides are organic compounds formed by the dehydration of amino acids and intermediate products of protein hydrolysis. Peptides have strong biological activity, which can regulate the functional activities of cells in living organisms, and play a variety of roles in medicine, cosmetics, food, and other fields. With the more and more extensive and in-depth applications […]
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  1. Biotech

BOC Sciences: A Robust Isotope Labeling Service Vendor

New York, United States—May 10, 2022—BOC Sciences is a robust supplier of stable isotope-labeled compounds in the United States. While realizing isotopic labeling with different molecules could be tricky sometimes, the company provides professional stable isotope labeling services for worldwide partners to support them from preclinical to commercial stages.   Stable isotope labeling involves the […]
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  1. Biotech

Complete Virtual Screening Solutions at BOC Sciences to Unleash Novel Drug Discovery Potential

New York, United States—May 17, 2022— Today, BOC Sciences released a complete set of virtual screening solutions to help partners maximize the diversity of hits using its ultra-large-scale purchasable compound libraries. As a robust method to identify promising drug candidates, virtual screening services provided by BOC Sciences not only minimize required experimental screening compounds but […]
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  1. Biotech

BOC Sciences Unveils Access to Comprehensive Set of PROTAC In Vitro Evaluation Services

New York, United States—May 27, 2022—BOC Sciences, a leading life science research and development company, today unveiled access to its full-scale PROTAC in vitro assessment services for biopharmaceutical clients and partners to expedite their PROTAC development from preclinical studies to clinical trials. With this advanced PROTAC development platform, BOC Sciences keeps solidifying its presence in […]
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  1. Biotech

Benefits of Stable Isotope Labelling in Biochemistry Research

Stable isotopes are a type of isotope whose radioactivity cannot be detected by naturally occurring techniques. In nature, the chemical and biological properties of stable isotopes compounds and the corresponding elements compounds are identical except for the mass number. Examples of stable isotopes mainly encompass deuterium, nitrogen-15, oxygen-18, and carbon-13. And stable isotope-labeled compounds are […]
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