Healthcare professionals use the drug Arsenic Trioxide to treat patients with acute promyelocytic leukemia (APL) who are refractory to or have relapsed from retinoid and anthracycline chemotherapy and whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression. Arsenic Trioxide is a sterile injectable solution, and it causes morphological changes and DNA fragmentation characteristic of apoptosis in NB4 human promyelocytic leukemia cells in vitro. Arsenic trioxide also causes damage or degradation of the fusion protein promyelocytic leukemia (PML) retinoic acid receptor (RAR)-alpha. The Arsenic Trioxide is supplied in single-dose vials of 10 mg to administer intravenously. One should store the drug Arsenic Trioxide at 25°C (77°F); excursions are permitted to 15 – 30°C (59 – 86°F). And one should not freeze the drug.
Arsenic Trioxide injection is readily available from several generic medicine suppliers at slightly varying prices. To know more about this drug, call us on 18008891064.
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